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Results 61 to 70 of about 4,891 (157)

Light‐Activatable Nitric Oxide Release via Intramolecular Electron Transfer for Tumor Pyroptosis Induction

Advanced Science, EarlyView.
This work proposes a novel strategy to fabricate unimolecular pyroptosis photoinitiators activated by deep‐red light at low light doses. It relies on a photosensitization mechanism to trigger nitric oxide (NO) release from benzisothiadiazole‐based N‐nitrosanilines without modification of nitro moieties, thereby boosting pyroptosis‐mediated ...
Chuangxin Zhang +4 more
wiley +1 more source

Hepatoma‐Derived Growth Factor Coordinates STAT3 Pathway and Exosome‐Mediated Intrahepatic Crosstalk to Control Hepatic Steatosis and MASLD

Advanced Science, EarlyView.
Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.
Jian Wen +28 more
wiley +1 more source

, 2017
With the use of folicullometry, the foliculles were measured in the experimental and control animals, which were divided in four groups according to the seasons.
ÐšÐ°Ð»Ð°Ð¼Ð°Ñ€Ð°Ñ (Kalamaras), ÐÐ½Ð° (Ana) +1 more
core

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon +20 more
wiley +1 more source

, 2018
The verification of the qualitative method with test devices for detection of eight drugs of abuse in urine (amphetamines, methamphetamine, barbiturates, benzoylecgonine, marijuana, 3,4-methylendioxy-methamphetamine, methadone, and opiates) was ...
Ð¢Ð¾ÑˆÐµÑÐºÐ°-Ð¢Ñ€Ð°Ñ˜ÐºÐ¾Ð²ÑÐºÐ° (Tosheska-Trajkovska), ÐšÐ°Ñ‚ÐµÑ€Ð¸Ð½Ð° (Katerina) +4 more
core

Faster and Durable: A Cell‐to‐System Validation of a Low‐Degradation Fast‐Charge Protocol for Li‐Ion Batteries

Advanced Science, EarlyView.
A physics‐based framework resolving graphite phase‐separation dynamics establishes a predictive, degradation‐aware fast‐charging methodology for commercial Li‐ion batteries. The resulting model‐informed protocol achieves 20%–80% state‐of‐charge in 14 min while matching the long‐term degradation of a commercial 25‐minute EV strategy.
Marco Lagnoni +10 more
wiley +1 more source

, 2017
Epidemiological data indicates that thyroid carcinoma (TC) is the most frequent endocrinological tumors, participating with around 1% from all malignomas.
ÐœÐ°ÐºÐ°Ð·Ð»Ð¸ÐµÐ²Ð° (Makazlieva), Ð¢Ð°ÑšÐ° (Tanja) +3 more
core

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang +10 more
wiley +1 more source

, 2017
Two sucker babies with fibrosa cystic have been presented: in one of them the disease was severe with the lethal outcome, while the other baby could be successfully treated.
Ð¡Ð¿Ð¸Ñ€Ð¾Ð²ÑÐºÐ¸ (Spirovski), Ð—Ð¾Ñ€Ð°Ð½ (Zoran) +2 more
core