Results 111 to 120 of about 6,069,835 (249)

Проценка на ризик за безбедноÑта на водата за пиење и водоÑнабдувањето во КичевÑкиот регион за периодот од 1996-2013 година

open access: yes, 2017
Intensification of systemic chemotherapy with in- clusion of high doses methotrexate (MTX) has contributed to the improvement of event-free survival in children with acute lymphoblastic leukemia (ALL). Despite this benefit, this agent might cause serious
ЕфтимијадоÑка (Eftimijadoska), Фани (Fani)
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Причини и поÑледици на повредите на градниот кош во мирновременÑки и воени уÑлови

open access: yes, 2017
We had 107 patients with chest injuries – 95 of them were blunt wounds and 12 were wounds from weapons (rifles, revolvers, shotguns, knives, bayonets ...).Chest injuries are, as serious in the peaceful-time, as in the military conditions. They bring into
Сарач (Sarach), Бранка (Branka)   +2 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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