Results 131 to 140 of about 6,249,924 (274)

« ‚ßÔÎ ×ð´ ×ñ˜æè Öæß

open access: hybrid, 2013
àææçÜ׿ ÌÕSâä×
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

ЦенÑÑалÑÐ½Ñ Ð¾Ñгани виконавÑÐ¾Ñ Ð²Ð»Ð°Ð´Ð¸ УкÑаÑни з обÑлÑговÑÐ²Ð°Ð½Ð½Ñ Ð¿Ð¾Ð²ÑÑÑÑного ÑÑÑÑ

open access: green, 2017
Юлія Леонідівна; Національний авіаційний університет Юринець   +1 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Association between vitamin D and serum uric acid in a large Chinese cohort of middle-aged and elderly Chinese men and women. [PDF]

open access: yesFront Nutr
Cao R   +12 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy