Results 201 to 210 of about 6,249,924 (274)

ÐÑганизаÑÐ¸Ñ ÐбÑединеннÑÑ ÐаÑий в ÑовÑеменной ÑиÑÑеме междÑнаÑодного пÑава

, 2016
Кристина Анатольевна Овчинникова
openalex   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Balanced polyunsaturated fatty acids diet prevents the D-galactose-induced neuroinflammation and cognitive impairments. [PDF]

Neurosci Appl
Marniquet I, Dupont-Viratelle J, Crespo F, Séré A, Layé S, Delpech JC.   +5 more
europepmc   +1 more source

ÐолоÑиÑÑика пÑиÑоднÑого ÑеÑедовиÑа ÑеÑÑонÑини в конÑекÑÑÑ Ð¿ÑоекÑÑÐ²Ð°Ð½Ð½Ñ ÐºÐ¾ÑÑÑÐ¼Ñ ÑегÑÐ¾Ð½Ñ Ñк заÑÐ¾Ð±Ñ Ð°ÑÑакÑÑÑ Ð² ÑÑÑизмÑ

, 2018
M. Artemenko
openalex   +1 more source

ÐÑенка ÑинанÑовой ÑÑÑойÑивоÑÑи пÑедпÑиÑÑиÑ(на пÑимеÑе ÐÐР«ÐÑиÑÑокÑÐ°Ñ 2»)

, 2017
Лолита Смайлиева
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Ugi multicomponent reactions of optically active aldehydes and chiral aminoindanols: diastereoselective synthesis of bisamides relevant to SARS-CoV-2 Mpro inhibitors.

Org Biomol Chem
Ghosh AK, Bhattacharjee A, Jayashankar U, Bogan SN, Mesecar AD.   +4 more
europepmc   +1 more source

P2X7R deficiency alleviates cardiac senescence by enhancing mitophagy via the HuR/TRIM26/NR4A1 axis. [PDF]

Clin Transl Med
Zhou Y, Zhong X, Mao Z, Chen Y, Xing J, Shen J, Zhang W, Zhang J, Mei J, Yang Z, Wang Z, Ye B, Lin J, Wang Y, Huang Z.   +14 more
europepmc   +1 more source

СкÑÐµÐ¼Ð±Ð»ÐµÑ Ð°Ð½Ð°Ð»Ð¾Ð³Ð¾Ð²ÑÑ Ñигналов на базе ÐЦРи ЦÐÐ Ñ Ð²ÐµÑовой избÑÑоÑноÑÑÑÑ

, 2009

openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source