Results 141 to 150 of about 5,874,305 (248)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Техники и методи за детекција и дијагноза на орални премалигни и малигни лезии

, 2015
Бруно Николовски, Danica Popovic Monevska, Ана Миновска, Мирјана Поповска, Vera Radojkova Nikolovska   +4 more
openalex  

Приложение на дигиталните технологии в обучението [PDF]

, 2020
Ð Ð ⁄ ð ̧РДÐμð ⁄ чÐμð
openalex  

Eye Salvage and Vision Preservation in High-Risk Intraocular Retinoblastoma Patients: Long-Term Results From the Prospective Phase II AIEOP RTB 012 Study. [PDF]

Cancer Med
Russo I, Di Ruscio V, De Ioris MA, Del Baldo G, De Pasquale MD, Valente P, Opocher E, Parrozzani R, Di Giannatale A, Cefalo MG, Serra A, Milano GM, Longo D, Carboni A, De Vito R, Natali G, D'Elia G, Bisogno G, Mastronuzzi A, Cozza R, Alaggio R, Romanzo A, Buzzonetti L, Locatelli F.   +23 more
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Улога на метаболичниот Ñиндром во развој и прогреÑија на хроничната бубрежна ÑлабоÑÑ‚

, 2015
Tatjana Barjaktarova Prosheva, Лилјана Тозија   +1 more
openalex  

Ð Ð¾Ð²Ð¸Ñ Ñ‚ Международен Ñ Ñ‚Ð°Ð½Ð´Ð°Ñ€Ñ‚ за Ñ„Ð¸Ð½Ð°Ð½Ñ Ð¾Ð²Ð¾ отчитане 17 и Ð¿Ñ€ÐµÐ´Ð¸Ð·Ð²Ð¸ÐºÐ°Ñ‚ÐµÐ»Ñ Ñ‚Ð²Ð°Ñ‚Ð° пред Ð·Ð°Ñ Ñ‚Ñ€Ð°Ñ…Ð¾Ð²Ð°Ñ‚ÐµÐ»Ð½Ð¸Ñ‚Ðµ компании [PDF]

, 2020
Ð Ð ÐμÐ ⁄ Ð ⁄ Ð ⁄ ра СтаР⁄ чÐμРа-ТР⁄ Ð ́Ð ⁄ рР⁄ Ра, РаР́Ñ Ð’ÐμÐ Ð ̧Ð ⁄ Ð ⁄ Ра-СР⁄ ÐoÐ ⁄ Ð Ð ⁄ Ра   +1 more
openalex  

Differential Astrocyte-Supplied NMDAR Co-Agonist for CA1 Versus Dentate Gyrus Long-Term Potentiation. [PDF]

Hippocampus
Sateesh S, Abraham WC.
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Efficacy of Spectacle Correction Using Defocus Incorporated Multiple Segments in the Myopic Population. [PDF]

Clin Ophthalmol
Zakova M, Fus M, Tejkl L.
europepmc   +1 more source