Results 41 to 50 of about 20,294,267 (243)

Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors

open access: yesAging Cell, 2016
Clearing senescent cells extends healthspan in mice. Using a hypothesis‐driven bioinformatics‐based approach, we recently identified pro‐survival pathways in human senescent cells that contribute to their resistance to apoptosis.
Yi Zhu   +13 more
semanticscholar   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus   +6 more
wiley   +1 more source

Little strings on D n orbifolds

open access: yesJournal of High Energy Physics, 2017
We explore two classes of 6d N = 1 0 $$ \mathcal{N}=\left(1,0\right) $$ little string theories obtained from type IIA/IIB NS5-branes probing D n singularities.
Joonho Kim, Kimyeong Lee
doaj   +1 more source

Ob etimologii i semantike termina voršud/vožšud [On the Etymology and Semantics of the Term voršud/vožšud]; pp. 276-282 [PDF]

open access: yesLinguistica Uralica, 2014
The paper deals with the concept of воршуд/вожшуд in the Udmurt language, which used to serve as a theonym for one of the traditional deities. The word was preserved by Udmurt local groups living in a foreign-language environment.
Nadežda Šutova
doaj   +1 more source

Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death

open access: yesScience, 2018
Caspase-8 is a player in pyroptosis The activation of certain pattern-recognition receptors by pathogen-associated molecular patterns results in the formation of inflammasome complexes.
Pontus Orning   +17 more
semanticscholar   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine   +10 more
wiley   +1 more source

Planck2015 results

open access: yesAstronomy & Astrophysics, 2016
This paper describes the mapmaking procedure applied to Planck Low Frequency Instrument (LFI) data. The mapmaking step takes as input the calibrated timelines and pointing information.
P. Ade   +258 more
semanticscholar   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga   +56 more
wiley   +1 more source

Degree sequence for k-arc strongly connected multiple digraphs

open access: yesJournal of Inequalities and Applications, 2017
Let D be a digraph on { v 1 , … , v n } $\{v_{1},\ldots, v_{n}\}$ . Then the sequence { ( d + ( v 1 ) , d − ( v 1 ) ) , … , ( d + ( v n ) , d − ( v n ) ) } $\{ (d^{+}(v_{1}), d^{-}(v_{1})), \ldots, (d^{+}(v_{n}), d^{-}(v_{n}))\}$ is called the degree ...
Yanmei Hong, Qinghai Liu
doaj   +1 more source

Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association

open access: yesCirculation, 2016
Author(s): Writing Group Members; Mozaffarian, Dariush; Benjamin, Emelia J; Go, Alan S; Arnett, Donna K; Blaha, Michael J; Cushman, Mary; Das, Sandeep R; de Ferranti, Sarah; Despres, Jean-Pierre; Fullerton, Heather J; Howard, Virginia J; Huffman, Mark D;
D. Mozaffarian   +41 more
semanticscholar   +1 more source

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