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Results 51 to 60 of about 5,874,305 (248)

ÐžÐ¡ÐžÐ‘Ð•ÐÐÐžÐ¡Ð¢Ð˜ Ð ÐÐ¡Ð§Ð•Ð¢Ð Ð¡Ð¢ÐžÐ˜ÐœÐžÐ¡Ð¢Ð˜ Ð—Ð•ÐœÐ•Ð›Ð¬ÐÐžÐ“Ðž Ð£Ð§ÐÐ¡Ð¢ÐšÐ Ð”Ð›Ð¯ Ð¡Ð¢Ð ÐžÐ˜Ð¢Ð•Ð›Ð¬Ð¡Ð¢Ð’Ð Ð˜ ÐžÐ‘Ð¡Ð›Ð£Ð–Ð˜Ð’ÐÐÐ˜Ð¯ Ð–Ð˜Ð›ÐžÐ“Ðž Ð”ÐžÐœÐ .

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source

ÐŸÐžÐ”Ð“ÐžÐ¢ÐžÐ’ÐšÐ Ð¡Ð¢Ð£Ð”Ð•ÐÐ¢ÐžÐ’ Ðš ÐŸÐ ÐžÐ¤Ð•Ð¡Ð¡Ð˜ÐžÐÐÐ›Ð¬ÐÐžÐ™ Ð˜ÐÐÐžÐ’ÐÐ¦Ð˜ÐžÐÐÐžÐ™ Ð”Ð•Ð¯Ð¢Ð•Ð›Ð¬ÐÐžÐ¡Ð¢Ð˜ Ð’ Ð ÐÐœÐšÐÐ¥ Ð¡ÐŸÐ•Ð¦Ð˜ÐÐ›Ð¬ÐÐžÐ“Ðž Ð£Ð§Ð•Ð‘ÐÐžÐ“Ðž ÐšÐ£Ð Ð¡Ð

Boundedness of strong maximal functions with respect to non-doubling measures

Journal of Inequalities and Applications, 2016
The main purpose of this paper is to establish a boundedness result for strong maximal functions with respect to certain non-doubling measures in R n $\mathbb{R}^{n}$ . More precisely, let d μ ( x 1 , … , x n ) = d μ 1 ( x 1 ) ⋯ d μ n ( x n ) $d\mu(x_{1},
Wei Ding, LiXin Jiang, YuePing Zhu
doaj +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

FEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai, Richard J. McDowell, Robert J. Lucas +2 more
wiley +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate +2 more
wiley +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source

Characterizing N-type derivations on standard operator algebras by local actions

AIMS Mathematics
On an infinite dimensional complex Hilbert space $ \mathcal{H} $, we consider a standard operator algebra $ \mathcal{S} $ with an identity operator $ I $ that is closed with respect to adjoint operation.
Khalil Hadi Hakami +3 more
doaj +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source

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