Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Е-кадеринот и неговата улога кај пациентки Ñо Ñерозен оваријален карцином во напреднат Ñтадиум [PDF]
, 2017 Ovarian cancer is the fifth leading cause of cancer deaths and has the highest mortality rate among gynecologic cancers in women in North America and Europe.The aim of this study wasto analyze the correlation between E-cadherin expression and clinical ...
ÐлулоÑки, Игор
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Фоликолометријата какао еден параметар за одредување на функцијата на тиреоидната жлезда под нормални и екÑпериментални уÑлови [PDF]
, 2017 With the use of folicullometry, the foliculles were measured in the experimental and control animals, which were divided in four groups according to the seasons.
ÐšÐ°Ð»Ð°Ð¼Ð°Ñ€Ð°Ñ (Kalamaras), Ðна (Ana) +1 more
core +1 more source
Contemporary Views of Iron Homeostasis with Main Focus of Hepcidin - New Hormone Regulator of Iron Metabolism [PDF]
, 2015 Железото е еÑенцијален елемент за Ñкоро Ñите живи организми. Тој е клучен функционален дел на киÑлородните транÑпортери, депонирачките моР...
Ilkovska, Biljana +2 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Когнитивниот дефицит кај возраÑни пациенти по анеÑтезија во не–кардијалната хирургија [PDF]
, 2017 Studies of the early 21st century indicate that the decline in cognitive functionis as a complication of anesthesia and operative intervention. Whether there would be changes and the amount of changes in mental status will cause a type of anesthesia is a
Трајкова, Радмила +2 more
core +1 more source
Risk Factors and Intensity of Dental Erosion of Permanent Incisors and the First Permanent Molars [PDF]
, 2015 ЦЕЛ: Целта на на нашата пилот Ñтудија беше да Ñе утврди преваленцата на забните ерозии, како и влијанието пијалоците врз Ñтепенот на оштетува
Denkova, Natasha, Iljovska, Snezhana
core +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
ДејÑтво на интерферон врз фагоцитоза на леукоцитите во in vitro уÑлови [PDF]
, 2016 In atempt to get elementary insight of interpheron action on leukocyte fagocytable capacity, in vitro were tested fagocytes from the patients with various diseases.
УгринÑки (Ugrinski), Предраг (Predrag) +1 more
core +1 more source