Results 71 to 80 of about 6,167,152 (219)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

N. A. Polevojaus laiškai S. D. Poltorackiui

Literatūra (Vilnius), 1966
Nikolajus Aleksejevičius Polevojus (1796–1846), žinomas „Maskvos telegrafo" redaktorius ir leidėjas, vienas iš žymesniųjų V. G. Belinskio pirmtakų, rusų XIX a. literatūroje buvo antidvarininkiškos literatūros kritikos pradininkas. Jis pradėjo
V. Salinka
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Паралелни иÑпитувања на еÑтрадиолот, прогеÑтеронот, ФСХ и ЛХ за време на менÑтруалниот циклуÑ

, 2017
The levels of estradiol, progesterone and gonadotropins were determined by radioimmunoassay in 8 healthy women, aging 18-22 years, with histories of regular menstruation.
ЧевреÑка (Chevreska), Стевка (Stevka), ДеловÑка (Delovska), ВеÑна (Vesna)   +1 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Загадочное зырянское слово абутор ’медведь-самец в пору течки’ [A Mysterious Komi Zyrian Word: абутор ’male bear in heat’] [PDF]

Linguistica Uralica
The paper investigates the Russian dialectal word абутор ’male bear in heat’ and its later fixation абуторь ’walking (not hibernating) bear’. The author proposes to discuss its new interpretation.
Galina Fedyuneva
doaj   +1 more source

ÐšÐ»Ð¸Ñ€ÐµÐ½Ñ Ð½Ð° I-131 и Ts-99 во тиреоидеа кај Ñтаорец

, 2017
Thyroid clearance of J-131 and Tc-99m after simultaneous subcutaneous injection in rats were estimated in the early phase. Arterial blood samples were drawn with a polyethene catheter inserted in the iliac artery in intervals of two minutes.
Таџер (Tadzher), ИÑак (Isak), ГеоргиевÑки (Georgievski), Славко (Slavko)   +1 more
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

New Spanish Dinotrema species with propodeal areola or mainly sculptured propodeum (Hymenoptera, Braconidae, Alysiinae)

ZooKeys, 2013
The illustrated descriptions of eight new species of the genus Dinotrema with either the propodeum mainly sculptured ora large propodeal areola from Spain are provided, viz. D. amparoae sp. n., D. benifassaense sp. n., D. lagunasense sp. n., D.
Francisco Javier Peris Felipo, Sergey Belokobylskij, Ricardo Jimenez   +2 more
doaj   +1 more source