Results 201 to 210 of about 6,270,767 (256)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Safety of intravenous neridronate in pediatric patients: insights from the monocentric retrospective NAPOLEON cohort. [PDF]

Ther Adv Musculoskelet Dis
Costi S, Amati A, Di Taranto R, Baldo F, Crotti C, Ricci M, Giani T, Gattinara MV, Varenna M, Caporali R, Chighizola CB, Marino A.   +11 more
europepmc   +1 more source

РеконÑÑÑÑкÑÐ¸Ñ ÑÑÑаÑенного памÑÑника аÑÑ Ð¸ÑекÑÑÑÑ Ð² виÑÑÑалÑной ÑÑеде

, 2017
Ярослав Юрьевич Шинкаренко
openalex   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia. [PDF]

Nat Commun
Mirfakhar FS, Marsh JA, Sato C, Schache KJ, Minaya MA, Dolle RE, Pak SC, Silverman GA, Perlmutter DH, Macauley SL, Karch CM.   +10 more
europepmc   +1 more source

ÐÑганизаÑÐ¸Ñ ÐбÑединеннÑÑ ÐаÑий в ÑовÑеменной ÑиÑÑеме междÑнаÑодного пÑава

, 2016
Кристина Анатольевна Овчинникова
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Inflammatory arthritis irAE may represent a unique autoimmune disease primarily driven by T cells but likely not autoantibodies. [PDF]

Sci Adv
Zhu X, Yu Y, Chen S, Langenfeld HE, Li Y, Wang P, Li Y, McCabe C, Hanson AC, Sharp BE, Woltzen A, Markovic SN, Davis JM, Dong H, Crowson CS, Thanarajasingam U, Zeng H.   +16 more
europepmc   +1 more source

ÐолоÑиÑÑика пÑиÑоднÑого ÑеÑедовиÑа ÑеÑÑонÑини в конÑекÑÑÑ Ð¿ÑоекÑÑÐ²Ð°Ð½Ð½Ñ ÐºÐ¾ÑÑÑÐ¼Ñ ÑегÑÐ¾Ð½Ñ Ñк заÑÐ¾Ð±Ñ Ð°ÑÑакÑÑÑ Ð² ÑÑÑизмÑ

, 2018
M. Artemenko
openalex   +1 more source

ÐÑенка ÑинанÑовой ÑÑÑойÑивоÑÑи пÑедпÑиÑÑиÑ(на пÑимеÑе ÐÐР«ÐÑиÑÑокÑÐ°Ñ 2»)

, 2017
Лолита Смайлиева
openalex   +1 more source