Results 41 to 50 of about 6,074,365 (261)

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Pofessor D. J. van Rooy- 'n waardering

open access: yesKoers : Bulletin for Christian Scholarship, 1956
So ken ons vir Dirk Jan van Rooy. Deur sy wysheid is hy ’n toring van krag in elke kring waarin hy hom beweeg.
W. P. Robbertse
doaj   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Anti-N-Methyl-D-Aspartate Receptor Encephalitis

open access: yesPediatric Neurology Briefs, 2013
Investigators at Universities of Barcelona, Pennsylvania, Oviedo, and Valencia, and the Spanish NMDAR Encephalitis Work Group report the clinical features of 20 pediatric patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis seen in a ...
J Gordon Millichap
doaj   +1 more source

N $$ \mathcal{N} $$ -extended D = 4 supergravity, unconventional SUSY and graphene

open access: yesJournal of High Energy Physics, 2020
We derive a 2+1 dimensional model with unconventional supersymmetry at the boundary of an AdS4 N $$ \mathcal{N} $$ -extended supergravity, generalizing previous results. The (unconventional) extended supersymmetry of the boundary model is instrumental in
L. Andrianopoli   +6 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Anti-N-Methyl-d-Aspartate Receptor Encephalitis

open access: yesPediatrics and Neonatology, 2011
Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a treatment-responsive encephalitis associated with anti-NMDA receptor antibodies, which bind to the NR1/NR2 heteromers of the NMDA receptors.
Te-Yu Hung, Ning-Hui Foo, Ming-Chi Lai
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Pervyj opyt perevoda Evangelija ot Ioanna na udmurtskij jazyk: grafiko-orfografičeskij analiz [Abstract. Graphical and Spelling Analysis of the Handwritten Gospel of St. John in Udmurt]; pp. 276-283 [PDF]

open access: yesLinguistica Uralica, 2012
The article deals with the features of spelling of the handwritten Gospel of St. John in the Udmurt language. The graphic and elements of spelling used in the Gospel are based on those of the first Udmurt grammar printed in 1775 under the title ”Soà ...
L. M. Ivšin
doaj   +1 more source

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