Results 151 to 160 of about 5,873,848 (258)

ÐŸÑ€ÐµÐ´Ð¸Ð·Ð²Ð¸ÐºÐ°Ñ‚ÐµÐ»Ñ Ñ‚Ð²Ð° при проектиране, изграждане и ÐµÐºÑ Ð¿Ð»Ð¾Ð°Ñ‚Ð°Ñ†Ð¸Ñ Ð½Ð° Ð¿Ð°Ñ Ð¸Ð²Ð½Ð° Ñ Ð³Ñ€Ð°Ð´Ð° в Ð‘ÑŠÐ»Ð³Ð°Ñ€Ð¸Ñ [PDF]

, 2020
Ð ̄Ð Ð ⁄ Ñ€ СтР⁄ Ñ Ð ⁄ Ð ⁄ Ð
openalex  

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Beyond the surface of capacity building: a mixed-methods study of the core functions and forms of dissemination and implementation science consultations. [PDF]

Implement Sci Commun
Swanson KN, Stadnick NA, Aarons GA, Brookman-Frazee L, Bouchard I, Du Z, Brubaker AG, Geremia C, Cain K, Conradi LR, Sklar M, Viglione C, Rabin BA.   +12 more
europepmc   +1 more source

Техники и методи за детекција и дијагноза на орални премалигни и малигни лезии

, 2015
Бруно Николовски, Danica Popovic Monevska, Ана Миновска, Мирјана Поповска, Vera Radojkova Nikolovska   +4 more
openalex  

Приложение на дигиталните технологии в обучението [PDF]

, 2020
Ð Ð ⁄ ð ̧РДÐμð ⁄ чÐμð
openalex  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Combinative Protein Expression of Immediate Early Genes c-Fos, Arc, and Npas4 Along Aversive and Appetitive Experience-Related Neural Networks. [PDF]

Hippocampus
Arai M, Osanai H, Snell CC, Gawf KE, Kitamura T, Ogawa SK.   +5 more
europepmc   +1 more source

Улога на метаболичниот Ñиндром во развој и прогреÑија на хроничната бубрежна ÑлабоÑÑ‚

, 2015
Tatjana Barjaktarova Prosheva, Лилјана Тозија   +1 more
openalex  

Ð Ð¾Ð²Ð¸Ñ Ñ‚ Международен Ñ Ñ‚Ð°Ð½Ð´Ð°Ñ€Ñ‚ за Ñ„Ð¸Ð½Ð°Ð½Ñ Ð¾Ð²Ð¾ отчитане 17 и Ð¿Ñ€ÐµÐ´Ð¸Ð·Ð²Ð¸ÐºÐ°Ñ‚ÐµÐ»Ñ Ñ‚Ð²Ð°Ñ‚Ð° пред Ð·Ð°Ñ Ñ‚Ñ€Ð°Ñ…Ð¾Ð²Ð°Ñ‚ÐµÐ»Ð½Ð¸Ñ‚Ðµ компании [PDF]

, 2020
Ð Ð ÐμÐ ⁄ Ð ⁄ Ð ⁄ ра СтаР⁄ чÐμРа-ТР⁄ Ð ́Ð ⁄ рР⁄ Ра, РаР́Ñ Ð’ÐμÐ Ð ̧Ð ⁄ Ð ⁄ Ра-СР⁄ ÐoÐ ⁄ Ð Ð ⁄ Ра   +1 more
openalex  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source