Results 111 to 120 of about 416 (126)

Adaptive Autonomy in Microrobot Motion Control via Deep Reinforcement Learning and Path Planning Synergy

Advanced Intelligent Systems, EarlyView.
This study introduces a data‐driven framework that combines deep reinforcement learning with classical path planning to achieve adaptive microrobot navigation. By training a surrogate neural network to emulate microrobot dynamics, the approach improves learning efficiency, reduces training time, and enables robust real‐time obstacle avoidance in ...
Amar Salehi, Bairong Zhu, Haoyu Liu, Tingting Yu   +3 more
wiley   +1 more source

Rüdin's Unpublished Family Study From the Early 1920s: “On the Inheritance of Manic‐Depressive Insanity”

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Ernst Rüdin, an important and controversial figure in the history of psychiatric genetics, published only one major empirical study on siblings of dementia praecox (DP) probands in 1916. He conducted a parallel study of siblings of probands with manic‐depressive insanity (MDI), but the resulting monograph, written in the early 1920s, was left ...
Kenneth S. Kendler, Astrid Klee
wiley   +1 more source

Diverse Genetic Etiologies of Unilateral Polymicrogyria

Annals of Neurology, EarlyView.
Objective Polymicrogyria (PMG) is one of the most common human malformations of cortical development and is often classified by its radiographic pattern of distribution. Unilateral polymicrogyria (uPMG) is a subtype of PMG affecting a portion or all of one cerebral hemisphere.
Abbe Lai, Jennifer E. Neil, Shyam K. Akula, Dina Amrom, Eva Andermann, Ann Bergin, Roberto Caraballo, Allen Y. Chen, John Gaitanis, Ganeshwaran H. Mochida, Jill M. Gotoff, Giorgi Kuchukhidze, Daphna Marom, Christelle Moufawad ElAchkar, Miriam Regev, Lance H. Rodan, Heather Olson, Bo Zhang, Annapurna Poduri, Diane D. Shao, Christopher A. Walsh, Edward Yang   +21 more
wiley   +1 more source

Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort

Annals of Neurology, EarlyView.
Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov, Ivana Dzinovic, Theresa Brunet, Vicente A. Yépez, Florian Hölzlwimmer, Elisabetta Indelicato, Birgit Assmann, Susann Badmann, Diana Ballhausen, Steffen Berweck, Felix Brechtmann, Melanie Brugger, Kevork Derderian, Felix Distelmaier, Philip Harrer, Denisa Harvanova, Petra Havrankova, Ann‐Kathrin Jaroszynski, Miriam Kolnikova, Robert Kopajtich, Anne Koy, Magdalena Krygier, Lukas Kunc, Katarina Kusikova, Oliver Maier, Maria Mazurkiewicz‐Bełdzińska, Christian Mertes, Ava Oberlack, Timo Roser, Alexandra Sitzberger, Ugo Sorrentino, Antonia M. Stehr, Katharina Vill, Matias Wagner, Holger Prokisch, Sylvia Boesch, Jan Necpal, Robert Jech, Juliane Winkelmann, Elisabeth Graf, Julien Gagneur, Matej Skorvanek, Michael Zech   +42 more
wiley   +1 more source

Acid‐ and Nucleophile‐Gated Photoisomerization of Phosphaindirubin

Angewandte Chemie, EarlyView.
Triply gated isomerization: In polar solvents, a phosphorus‐containing indirubin photoswitch undergoes visible‐light‐driven Z→E isomerization only when protonated, and reverts thermally via nucleophile‐catalyzed back‐isomerization. This three‐way control by light, acid, and nucleophile enables reversible photoisomerization.
Jacob Jan van der Wal, Jorn D. Steen, Ann‐Kathrin Rückert, Roman Yu. Peshkov, Michiel F. Hilbers, P. Tim Prins, Wybren Jan Buma, Andreas Orthaber, Stefano Crespi   +8 more
wiley   +1 more source

Mechanically Triggered Chemical Recyclable Polyethylene‐Like Materials

Angewandte Chemie, EarlyView.
Polyethylene‐like copolymers with benchmark properties are prepared by embedding latent cyclobutene mechanophores to overcome PE's end‐of‐life limits. The mechanophores are inert in service but are selectively opened by solvent‐free ball milling to yield well‐defined telechelic oligomers.
Menghe Xu, Peng Liu, Changle Chen, Tae‐Lim Choi   +3 more
wiley   +1 more source

Tetraaza[7]–[15]helicenes Synthesized by Two‐Step Strategy: Length‐Controlled Chiral π‐Systems Exhibiting Amplified Circularly Polarized Luminescence

Angewandte Chemie, EarlyView.
A modular two‐step strategy provides tetraaza[n]helicenes (n = 7–15) as a homologous series with tunable photophysical and chiroptical properties. Extension beyond n = 11 induces pronounced through‐space π–π interactions, narrowing the energy gap and amplifying circularly polarized luminescence.
Takashi Otani, Yuchen Wu, Kohei Ueda, Yuki Ikeda, Yuna Tada, Natsuna Kinoshita, Takanori Shibata   +6 more
wiley   +1 more source

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Digital Technologies for Scientific Analysis of Current Data on the Epidemic of New Coronavirus Infection COVID-2019

Legal Concept, 2020
DIGITAL TECHNOLOGIES FOR SCIENTIFIC ANALYSIS OF CURRENT DATA ON THE EPIDEMIC OF NEW CORONAVIRUS INFECTION COVID-2019Alternate : Сегодня человечество столкнулось с новым большим вызовом, Ð¼Ð°ÑÑˆÑ‚Ð°Ð±Ð½Ñ ...
A. Inshakova
semanticscholar   +1 more source

A facile access to 2-methylthio/alkoxy/amino-3-acylimidazo[1, 2-a]pyridines based on cupric chloride promoted oxidative ring closure of alpha-oxoketene N,S-, N,O-, and N,N-acetals.

Journal of Organic Chemistry, 2000
O. Barun, H. Ila, H. Junjappa, O. Singh
semanticscholar   +1 more source

Lack of effect of vitamin D3 supplementation in autism: a 20-week, placebo-controlled RCT

Archives of Disease in Childhood, 2017
C. Kerley, Clare Power, L. Gallagher, D. Coghlan   +3 more
semanticscholar   +1 more source