Results 101 to 110 of about 428 (171)

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

open access: yesAdvanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu   +9 more
wiley   +1 more source

Hollow Cholesteric Liquid Crystal Elastomer Fiber with Synergistically Enhanced Resilience and Mechanochromic Sensitivity

open access: yesAdvanced Science, EarlyView.
It describes hollow cholesteric liquid crystal elastomer fiber with radial helix prepared by solvent evaporation‐induced assembly and template assistance. The fiber show mechanochromic wavelength blueshift of 2.25 nm·%−1 under low strain. Excellent mechanochromic reversibility and resilience are devoted by cross‐linking in the wall layer.
Wenwen Wang   +8 more
wiley   +1 more source

Subgenome Partitioning and Polyploid Genome Evolution in the Loach Family Botiidae (Order Cypriniformes)

open access: yesAdvanced Science, EarlyView.
This study investigates subgenome evolution and polyploidy in Cypriniformes fish, revealing complex phylogenetic relationships and genomic dynamics. By applying advanced subgenome partitioning methods, it uncovers novel insights into transposon activity and gene fractionation.
Yunyun Lv   +14 more
wiley   +1 more source

UTX Responds to Nanotopography to Suppress Macrophage Inflammatory Response by Remodeling H3K27me3 Modification

open access: yesAdvanced Science, EarlyView.
Compared with those on the pTi surface, macrophages on the TNTs surface present reduced myosin II contractility, which facilitates the nuclear translocation of the UTX. This reduction decreases the enrichment of the repressive H3K27me3 histone modification at the Abca1 gene locus, which promotes the transcription and protein expression of ABCA1 ...
Hengji Jia   +8 more
wiley   +1 more source

Programmable DNA‐Based Molecular Neural Network Biocomputing Circuits for Solving Partial Differential Equations

open access: yesAdvanced Science, EarlyView.
This research introduces an augmented matrix‐based DNA molecular neural network to achieve molecular‐level solving of biological Brusselator PDEs. Crucial innovations include: (i) an augmented matrix‐based DNA molecular neural network, enabling multidimensional parameter integration through DNA strand displacement cascades and iterative weight ...
Yijun Xiao   +5 more
wiley   +1 more source

Heme/NADH Mimics Co‐Decorated Allosteric Capsules for Regulating Oxygen Activation and Upregulating Intracellular Methionine Depletion

open access: yesAdvanced Science, EarlyView.
Through modifying the switchable µ‐oxo bridged FeIII‐porphyrins moiety and NADH mimics into a metal‐organic capsule, multiple responsive manners for O2 activation, chemical oxygenation and metabolic transformation have been demonstrated for upregulating intracellular methionine depletion and accumulation of methionine sulfoxide to achieve effective ...
Chunming Ma   +5 more
wiley   +1 more source

Дизморфофобија и еÑтетÑка хирургија

open access: bronze, 2015
Marija Miloshevska MijalkovsÐoa   +3 more
openalex  

Tuning the Organic Electrochemical Transistor (OECT) Threshold Voltage with Monomer Blends

open access: yesAdvanced Electronic Materials, EarlyView.
A novel approach is introduced to modulate the threshold voltage of organic electrochemical transistors (OECTs) through the copolymerization of monomers with differently charged sidechains. We demonstrate that blends of water‐soluble tri‐thiophene compounds with anionic and zwitterionic sidechains form compositionally uniform aggregates at different ...
Diana Priyadarshini   +13 more
wiley   +1 more source

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