Results 131 to 140 of about 428 (171)
American Journal of Hematology, EarlyView.ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov +2 more
wiley +1 more source
A Novel Merocyanine Derivative for Probing Polarity at Cubosome Interfaces
Asian Journal of Organic Chemistry, EarlyView.This study develops a synthetic route to C10SP, a polarity‐sensitive sensor embedded in phytantriol‐based cubosomes. Strategic steps included tertiary amine‐mediated amidation to covalently attach a hydrophobic tail and controlled nitrogen methylation to form the iminium moiety within the indolenine scaffold.
Marcelo J. Eberhardt +3 more
wiley +1 more source
Diglycerides of Natural Phenols and Organic Acids for Enhanced Biological Activities
Asian Journal of Organic Chemistry, EarlyView.Diglycerides of natural organic acids and phenols were synthesized regio‐selectively. Diglycerides are structurally similar to cell membranes and are expected to exhibit cell affinity and permeability. The flexible glycerol linkers allow the diglycerides to exhibit not only the physiological activities of each constituent organic acid but also the ...
Jisu Hong +10 more
wiley +1 more source
Synthesis of Benzodithieno[5.5.5.6]Fenestranes: Unexpected Epimerization and Regiochemical Outcomes
Asian Journal of Organic Chemistry, EarlyView.Isomeric [5.5.5.6]fenestranes annulated with one benzene and two thiophene rings are accessible via di‐2‐ and di‐3‐thienylspirane intermediates. The key double cyclization step involves surprising stereoselectivity and regioselectivity. In particular, cis‐di(2‐thienyl)spirane precursors lead to the all‐cis‐fenestrane skeleton by an unexpected acid ...
Björn Bredenkötter +5 more
wiley +1 more source
4,6‐O‐Phenylboronic Ester Protection for 1,2‐cis‐α‐Selective Glucosylation
Asian Journal of Organic Chemistry, EarlyView.The 4,6‐O‐phenylboronic ester protection for 1,2‐cis‐α‐selective glucosylation, previously reported by the Crich group, was revisited and the stereodirecting effect of the cyclic protecting group was unveiled. 4,6‐O‐Phenylboronic ester‐protected glucosyl and 2‐azido‐2‐deoxyglucosyl donors exhibited higher α‐selectivity of the glucosylation than the ...
Yuta Umemura +6 more
wiley +1 more source
Asian Journal of Organic Chemistry, EarlyView.Compact N,N‐diphenylaminophenyl–quinoxaline donor–acceptor‐type dyes were synthesized, and the effects of substituents on the fluorescence properties were investigated. Introduction of electron‐withdrawing groups to the quinoxaline acceptor caused a red shift of the emission, and furthermore, thermally activated delayed fluorescence was facilitated by ...
Masaki Nagaoka +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.A rare sequence‐selective terpolymerisation of elemental sulphur, aromatic thioanhydrides, and epoxides yields dynamic poly(ester‐alt‐Sx) polymers. Mechanistic insights reveal a lithium‐catalysed rate enhancement via ester coordination. The resulting polymers are thermally stable, backbone‐editable, and processable into degradable adhesives.
Cesare Gallizioli +2 more
wiley +2 more sources
Tuning Antiaromaticity Through Meso‐Substituent Orientation in Core‐Modified Isophlorins
Asian Journal of Organic Chemistry, EarlyView.The antiaromaticity of dithiadioxaisophlorins is controlled by the steric bulkiness of meso‐substituents through their tilt angle relative to the macrocycle. Bulkier substituents maintain larger angles, preserving stronger antiaromaticity, while smaller groups facilitate π‐conjugation with the macrocycle, diminishing antiaromaticity.
Maika Isoda +3 more
wiley +1 more source
HCN2‐Associated Neurodevelopmental Disorders: Data from Patients and Xenopus Cell Models
Annals of Neurology, EarlyView.Objective We aimed to characterize the phenotypic spectrum and functional consequences associated with variants in HCN2, encoding for the hyperpolarization‐activated cyclic nucleotide (HCN) gated channel 2. Methods GeneMatcher facilitated the recruitment of 21 individuals with HCN2 variants from 15 unrelated families, carrying HCN2 variants.
Clara Houdayer +52 more
wiley +1 more source
Angewandte Chemie, EarlyView.Fe2N cluster liganded single‐atom Fe‐N‐C catalyst was made via impending the conventional thermal atomization process. The in situ generated Fe2N clusters can optimate the electronic structures of Fe‐N4 sites, thereby rendering Fe2Nnc/Fe1‐N‐C catalyst a record‐high oxygen reduction activity of 0.957 V versus RHE in alkali condition.
Fei‐Xiang Ma +8 more
wiley +1 more source