Results 81 to 90 of about 428 (171)

Novel ATR/PARP1 Dual Inhibitors Demonstrate Synergistic Antitumor Efficacy in Triple‐Negative Breast Cancer Models

open access: yesAdvanced Science, EarlyView.
Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao   +13 more
wiley   +1 more source

Classical Path Methods in Line Broadening. I. The Classical Path Approximation. [PDF]

open access: yesJ Res Natl Bur Stand A Phys Chem, 1969
Smith EW, Vidal CR, Cooper J.
europepmc   +1 more source

A Universal Approach to Anchoring Chromophores onto Magnetic Scaffold for Achieving Easily Recyclable Heterogeneous Photocatalytic Systems

open access: yesAdvanced Science, EarlyView.
The practical application of chromophores such as porphyrins, coumarins, anthraquinones, and pyrene derivatives in photocatalysis is severely limited by catalyst stability and reusability. In this work, a simple and universal strategy is presented for preparing highly efficient and recyclable heterogeneous photocatalysts for the oxidative coupling of ...
Xuan Zhan   +9 more
wiley   +1 more source

Living Biotherapeutics Using Nanoparticles‐Armed Cyanobacteria for Boosting Photodynamic‐Immunotherapy of Cancer

open access: yesAdvanced Science, EarlyView.
A schematic illustration of the cyanobacteria‐based biohybrid platform for photodynamic cancer therapy enhanced PDT. The platform continuously outputs O2 (to alleviate tumor hypoxia) and 1O2 (for tumor treatment), achieving improved photodynamic immunotherapy. Abstract The interdisciplinary development of synthetic biology and material sciences propels
Zhengwei Xu   +14 more
wiley   +1 more source

Single‐Cell RNA Sequencing Identifies MMP11+ Cancer‐Associated Fibroblasts as Drivers of Angiogenesis and Bladder Cancer Progression

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing identifies MMP11⁺ CAFs as pro‐angiogenic cells accumulating during bladder cancer progression. These cells promote angiogenesis by regulating ESM1⁺ tip endothelial cells and recruiting SPP1⁺ macrophages. Tumor‐derived BMP2 promotes their activation.
Wuwu Xu   +13 more
wiley   +1 more source

Bio‐Inspired Strategy for Radiation‐Based Thermal Management and Utilization

open access: yesAdvanced Science, EarlyView.
Biological organisms have evolved remarkable strategies to manage and exploit thermal radiation. This review explores bio‐inspired systems that mimic these adaptations—such as radiative cooling, thermal regulation, thermal insulation, water harvesting, infrared camouflage, and infrared detection—and highlights their application in thermal management ...
Hyung Rae Kim   +5 more
wiley   +1 more source

Performance of ginger constituents against SARS-CoV-2 virus: A therapeutic and theoretical approach. [PDF]

open access: yesParasite Epidemiol Control
Kadhim MM   +4 more
europepmc   +1 more source

The rheostat in the membrane: BCL-2 family proteins and apoptosis

open access: yesCell Death and Differentiation, 2013
N. Volkmann   +3 more
semanticscholar   +1 more source

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