Results 81 to 90 of about 109 (109)
British Journal of Haematology, EarlyView.Summary Despite evidence‐based guidelines to inform platelet transfusion practice, unnecessary platelet transfusion persists. We performed a multicentre retrospective analysis of adults admitted to general medicine, subspecialty medicine and critical care from 1 January 2017 to 30 June 2022.
Sarah Ryan +14 more
wiley +1 more source
From tetrachoric to kappa: How to assess reliability on binary scales
British Journal of Mathematical and Statistical Psychology, EarlyView.Abstract Reliability is crucial in psychometrics, reflecting the extent to which a measurement instrument can discriminate between individuals or items. While classical test theory and intraclass correlation coefficients are well‐established for quantitative scales, estimating reliability for binary outcomes presents unique challenges due to their ...
Sophie Vanbelle
wiley +1 more source
Boreas, EarlyView.We present a 25‐stage reconstruction of the ice‐flow pattern evolution of the Scandinavian Ice Sheet based on mapping and analysis of ~240 000 subglacial lineations and lineation fields across Norway, Sweden, Finland, and parts of NW Russia. Our reconstruction uses a glacial geomorphological inversion approach, in which we generated 611 individual ...
Frances E. G. Butcher +9 more
wiley +1 more source
Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway
British Journal of Pharmacology, EarlyView.Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu +4 more
wiley +1 more source
What Linked Data Can Tell Us About the Increasing Numbers of Children Entering Public Care
Child &Family Social Work, EarlyView.ABSTRACT The number of children in public care in Wales, UK, rose from the mid‐1990s to 2021. It is unclear if this change was related to increases in risk factors in parents, changes in the impact of risk factors, or changing policies and practices.
Nell Warner +4 more
wiley +1 more source
On Schopenhauer's Debt to Spinoza1
European Journal of Philosophy, EarlyView.Abstract Schopenhauer offers ‘nature is not divine but demonic’ as a direct rebuttal of Spinoza's pantheism, his identification of ‘nature’ with ‘God’. And so, one would think, he ought to have been immune to the ‘Spinozism’ that became, as Heine called it, ‘the unofficial religion’ of the age.
Julian Young
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Timely diagnosis and effective treatment of Lennox–Gastaut syndrome (LGS) improve prognosis and lower health care costs, but the transition from infantile epileptic spasms syndrome (IESS) to LGS is highly variable and insidious. Objective biomarkers are needed to monitor this progression and guide clinical decision‐making. Methods We
Blanca Romero Milà +11 more
wiley +1 more source
Epilepsia, EarlyView.Graphical representation of article highlights, including early response rates with adjunctive cenobamate. Abstract Objective To examine early responses to cenobamate therapy using prospective data from a dose–response study in Asian patients with focal seizures (YKP3089C035, C035) that employed a titration regimen starting at 12.5 mg/day.
Kensuke Kawai +19 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Although vagus nerve stimulation (VNS) is a well‐established neuromodulation therapy for drug‐resistant epilepsy, treatment outcomes remain heterogeneous. One possible source of variability lies in differing interpretations of seizure frequency ratings (SFRs).
Thiemo F. Dinger +44 more
wiley +1 more source