Results 1 to 10 of about 68,470 (139)

Two Years of Ocrelizumab Treatment in Black and Hispanic People with Multiple Sclerosis in CHIMES: A Single-Arm Clinical Trial. [PDF]

Ann Neurol
Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Amezcua L, Reder AT, Bernitsas E, Monson NL, Vartanian T, Wu GF, Saleh M, Okai A, Obeidat AZ, Sokhi D, Parekh R, Pei J, Harp C, Clayton D, Abioye I, Williams MJ, CHIMES Study Group.   +16 more
europepmc   +2 more sources

Òpera i sarsuela a Tarragona de 1850 a 1900 [PDF]

, 2017
[cat] El propòsit d'aquest projecte de tesi ha estat fer un estudi de camp sobre la vida lírica a la ciutat de Tarragona al llarg de la segona meitat del segle XIX.
Nadal Querol, Maria Josep
core   +4 more sources

Òpera en texans y This is opera al servicio de la educación musical [PDF]

, 2019
In recent times, the musical pedagogy uses the audiovisual to implement new didactic procedures. Among other, applications based on movies or television series, including video games, are common.
Montoya Rubio, Juan Carlos
core   +1 more source

Per una teoria de la subtitulació d'òpera : presentació de l'adaptació de subtítols de pantalla per a Òpera oberta [PDF]

, 2012
A partir de sis anys d'experiència en la subtitulació multilingüe d'òpera, en el marc del projecte Òpera oberta, liderat pel Gran Teatre del Liceu de Barcelona i en què va col·laborar la Facultat de Traducció i d'Interpretació de la Universitat Autònoma ...
Sala Sanahuja, Joaquim,
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Cavalleria rusticana ; Pagliacci [PDF]

, 1944
Cavalleria rusticana : òpera de Pietro Mascagni ; Pagliacci : òpera de Ruggero LeoncavalloDe cada obra s'ha digitalitzat un programa sencer. De la resta s'han digitalitzat les parts que són diferents.Direcció artística Empresa Juan Mestres CalvetEmpresa:
Leoncavallo, Ruggero, Anglada, Àngel, Civil, Pablo, Altube, Cristobal, Mascagni, Pietro, Torres, Raimundo, Campiña, Fidela, Societat del Gran Teatre del Liceu, Cabanes, Antonio   +8 more
core   +1 more source

Upscaling the Fabrication of Rod‐Shaped Microgels: A Microfluidic Method Combining Step‐Emulsification With Consecutive Droplet Confinement in Parallelized Microchannels

Advanced Materials, EarlyView.
A microfluidic method is presented which enables parallelized fabrication of rod‐shaped microgels, based on step‐emulsification (SE) droplet generation and subsequent droplet distribution and confinement, combined in a single device. Microgel rods are fabricated in parallel at different flow rates based on two light‐mediated crosslinking chemistries ...
Matthias Mork, Ninon Möhl, Greta Romahn, Laura Klasen, Cédric Bergerbit, Laura De Laporte   +5 more
wiley   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source