Results 51 to 60 of about 4,255,416 (197)
The purpose of the paper is to analyze the issue of applying by Ukraine of mechanisms developed in the legal framework by the World Trade Organization to protect the internal market in order to prepare appropriate recommendations to state power ...
Ivan Us
doaj
Judikatura ESLP k trestání sexuálního násilí: Dobré úmysly, špatné právo?
Článek kriticky diskutuje závěry dvou nedávných významných rozsudků Evropského soudu pro lidská práva (věci M.G. proti Litvě a Vučković proti Chorvatsku), které se týkají trestání sexuálního násilí.
Jakub Drápal
doaj +1 more source
La terminologia de la ciberseguretat: creació i ús en català
Amb la intenció de disposar d’alternatives catalanes per a la ingent creació de neologismes en l’àmbit de la ciberseguretat, el TERMCAT i l’Agència de Ciberseguretat de Catalunya han treballat conjuntament per sistematitzar i publicar la terminologia ...
Marta Grané Franch
doaj
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Choosing a coursebook for a particular group of students involves adapting the material against the context in which it is going to be used because it is easy to understand that most text books are produced for large-scale, commercial use, and therefore
Md. Shayeekh-Us-Saleheen
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source

