Results 1 to 10 of about 288,536 (293)

Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection.

JAMA pediatrics, 2022
Importance Associations between in utero exposure to maternal SARS-CoV-2 infection and neurodevelopment are speculated, but currently unknown. Objective To examine the associations between maternal SARS-CoV-2 infection during pregnancy, being born ...
Lauren C. Shuffrey, M. Firestein, M. Kyle, Andrea Fields, C. Alcántara, Dima Amso, J. Austin, J. Bain, J. Barbosa, Mary L. Bence, Catherine Bianco, Cristina R. Fernández, S. Goldman, C. Gyamfi‐Bannerman, Violet Hott, Yunzhe Hu, Maha Hussain, P. Factor-Litvak, M. Lucchini, Arthur M. Mandel, R. Marsh, D. McBrian, M. Mourad, R. Muhle, Kimberly G Noble, A. Penn, C. Rodriguez, A. Sania, Wendy G. Silver, Kally C. O'Reilly, M. Stockwell, Nim Tottenham, M. G. Welch, N. Zork, W. Fifer, C. Monk, D. Dumitriu   +36 more
semanticscholar   +1 more source

Ex utero monkey embryogenesis from blastocyst to early organogenesis.

Cell, 2023
The third and fourth weeks of gestation in primates are marked by several developmental milestones, including gastrulation and the formation of organ primordia.
Yandong Gong, Bing Bai, Nianqin Sun, Baiquan Ci, Honglian Shao, Ting Zhang, Hui-yu Yao, Youyue Zhang, Yuyu Niu, Lizhong Liu, Huiling Zhao, Hao Wu, Lei Zhang, Tianxiang Wang, Shangang Li, Yulei Wei, Yang Yu, A. Orsi, Bing Liu, W. Ji, Junqing Wu, Yongchang Chen, apple apple   +22 more
semanticscholar   +1 more source

Ionizable lipid nanoparticles for in utero mRNA delivery

Science Advances, 2021
Lipid nanoparticles deliver mRNA to mouse fetuses, which may ultimately enable in utero therapy to treat fetal genetic diseases. Clinical advances enable the prenatal diagnosis of genetic diseases that are candidates for gene and enzyme therapies such as
Rachel S. Riley, Meghana V. Kashyap, Margaret M. Billingsley, Brandon M. White, M. Alameh, S. Bose, P. Zoltick, Hiaying Li, R. Zhang, Andy Cheng, D. Weissman, W. Peranteau, M. J. Mitchell   +12 more
semanticscholar   +1 more source

Birth Outcomes of Neonates Exposed to Marijuana in Utero

JAMA Network Open, 2022
This systematic review and meta-analysis compares adverse neonatal outcomes among mothers exposed to marijuana during pregnancy vs mothers not exposed to marijuana during pregnancy in 16 cohort studies.
Greg J. Marchand, A. Masoud, M. Govindan, K. Ware, A. King, S. Ruther, G. Brazil, H. Ulibarri, J. Parise, A. Arroyo, C. Coriell, S. Goetz, Amitis Karrys, K. Sainz   +13 more
semanticscholar   +1 more source

In Utero Enzyme-Replacement Therapy for Infantile-Onset Pompe's Disease.

New England Journal of Medicine, 2022
Patients with early-onset lysosomal storage diseases are ideal candidates for prenatal therapy because organ damage starts in utero. We report the safety and efficacy results of in utero enzyme-replacement therapy (ERT) in a fetus with CRIM (cross ...
Jennifer L. Cohen, P. Chakraborty, K. Fung-Kee-Fung, M. Schwab, D. Bali, S. Young, M. Gelb, H. Khaledi, A. DiBattista, S. Smallshaw, F. Moretti, Derek Wong, C. Lacroix, D. El Demellawy, Kyle C. Strickland, J. Lougheed, A. Moon‐Grady, B. Lianoglou, P. Harmatz, P. Kishnani, T. Mackenzie   +20 more
semanticscholar   +1 more source

Trasplante ortotópico de útero. Experimento en modelo ovino, Cali (Colombia)

Revista Colombiana de Obstetricia y Ginecología, 2020
Objetivo: se ha recomendado a los profesionales que tengan como proyecto realizar trasplante uterino, hacer previamente trabajos experimentales en animales.
Felipe Castro-Villegas, Gustavo Adolfo Canaval-Erazo, Juan Manuel Rico-Juri, José Óscar Gutiérrez-Montes, Anabel Vanin-Aguas, Hoover Orlando Canaval-Erazo   +5 more
doaj   +1 more source

Manejo de la hemorragia posparto en una paciente con útero bicorne con la sutura B-Lynch. Reporte de caso y revisión de la literatura

Revista Colombiana de Obstetricia y Ginecología, 2023
Objetivos: describir un caso de manejo con sutura de B-Lynch en una mujer con útero bicorne que presenta hemorragia posparto (HPP), y realizar una revisión de la literatura acerca de las estrategias de control quirúrgico de la HPP en pacientes con ...
Amanecer Rueda-Monsalbe, Jhon Edison Sanabria-Castelblanco, Miguel Ángel Montañez-Aldana   +2 more
doaj   +1 more source

Aspectos morfológicos específicos del útero del coipo (Myocastor coypus)

Analecta Veterinaria, 2021
La morfología de los órganos tubulares del aparato reproductor de las hembras del coipo difiere de las de otras especies de mamíferos, ya que presenta un útero doble. El objetivo de este trabajo fue ampliar los conocimientos sobre la morfología del útero
Antonio Felipe, Paula Alzola
doaj   +1 more source

Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery.

Journal of Controlled Release, 2021
Congenital disorders resulting in pathological protein deficiencies are most often treated postnatally with protein or enzyme replacement therapies. However, treatment of these disorders in utero before irreversible disease onset could significantly ...
K. Swingle, Margaret M. Billingsley, S. Bose, Brandon M. White, Rohan Palanki, A. Dave, Savan K Patel, N. Gong, Alex G. Hamilton, M. Alameh, D. Weissman, W. Peranteau, M. J. Mitchell   +12 more
semanticscholar   +1 more source

Viable bacterial colonization is highly limited in the human intestine in utero

Nature Medicine, 2020
Mucosal immunity develops in the human fetal intestine by 11–14 weeks of gestation, yet whether viable microbes exist in utero and interact with the intestinal immune system is unknown.
E. Rackaityte, J. Halkias, E. Fukui, V. Mendoza, C. Hayzelden, E. Crawford, K. Fujimura, T. Burt, S. Lynch   +8 more
semanticscholar   +1 more source