Results 161 to 170 of about 115,041 (194)

Maternal antibodies regulate the establishment of murine oral and salivary mucosal immunity. [PDF]

Nat Commun
Naamneh R, Attar Y, Netanely-Rimon Y, Jaber Y, Yacoub S, Saar O, Georgiev O, Kles P, Darawshi N, Bsoul R, Heinberg A, Eli-Berchoer L, Shapiro H, Elinav E, Wilensky A, Hovav AH.   +15 more
europepmc   +1 more source

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression

Cancer Science, EarlyView.
Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal, Laura Spinelli, Nisha Kriplani, Helen Wise, Nadege Poncet, Giulia Marzano, Karen E. Anderson, Katarzyna M. Grzes, Zofia Varyova, Mahreen Adil, C. Peter Downes, Phillip T. Hawkins, Len R. Stephens, Kate G. Storey, Doreen A. Cantrell, Bart Vanhaesebroeck, Nicholas R. Leslie   +16 more
wiley   +1 more source

Congenital cytomegalovirus infection drives oligoclonal expansion of cytotoxic γδ T cells from early fetal progenitors. [PDF]

J Immunol
Levan J, Vaaben AV, Tsui J, Davidson BR, Olive ME, Callaway PC, Nguyen CBT, Ilala M, Patel RK, Hunter RD, Fragiadakis GK, Combes AJ, Nankya F, Dorsey G, Kakuru A, Muhindo M, Feeney ME.   +16 more
europepmc   +1 more source

Parents With Substance Use Disorder in the Holding Tight Treatment System: Intervention Effectiveness and Moderating Effects

Child &Family Social Work, EarlyView.
ABSTRACT Parents with substance use disorder have multiple risks affecting their parenting. Mental health problems and adverse childhood experiences (ACEs) with problems in emotion regulation and adult attachment insecurity may impair the early interaction with the infant.
Saara J. Salo, Marjo Flykt, Yan Li, Mirjam Kalland, Marjukka Pajulo   +4 more
wiley   +1 more source

In-utero cell transplantation for hypophosphatasia with gene-edited hESC-derived MSCs in a murine model. [PDF]

Mol Ther Adv
Kitamura N, Hasegawa A, Takahashi-Nakamura A, Kasahara M, Akutsu H, Sago H, Samura O, Okamoto A, Umezawa A.   +8 more
europepmc   +1 more source

Editorial: Neurodevelopment: parental influences, <i>in utero</i> exposures, and genetics, volume II. [PDF]

Front Neurosci
Mohan KN.
europepmc   +1 more source

General Movement Assessment in infancy and later cognitive outcomes: A systematic review and meta‐analysis

Developmental Medicine &Child Neurology, EarlyView.
Aim To evaluate whether the General Movement Assessment (GMA) in infancy is associated with later cognitive outcomes from early childhood through adulthood. Method Cohort and case–control studies examining associations between Prechtl's GMA and cognitive outcomes from 6 months of age were eligible.
Sarah E. Hall, Caroline F. Alexander, Kaitlyn Turbett, Natasha Amery, Emily R. Young, Alison Salt, Sheau Huey Chen, Samudragupta Bora, Robert S. Ware, Catherine Elliott, Ashleigh Thornton, Jane Valentine   +11 more
wiley   +1 more source

Antenatal CFTR Modulators to Treat a Healthy Pregnant Woman with a Fetus Affected by Cystic Fibrosis Complicated by Meconium Ileus and Intestinal Volvulus: From a Suspicion of the Disease to a Targeted Treatment in Utero: Case Report and Narrative Review. [PDF]

J Clin Med
Montironi R, Giannubilo SR, Cappanera I, Capogrosso G, Mancinelli R, Rinci A, Ciavattini A.   +6 more
europepmc   +1 more source

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Maternal glycaemia and child educational attainment at age 5 in the Born in Bradford cohort

Diabetic Medicine, EarlyView.
Abstract Aims There is emerging evidence that maternal hyperglycaemia may be associated with adverse offspring neuro‐behavioural outcomes, which are foundational to educational success. We hypothesised that higher levels of maternal glucose would be associated with poorer educational attainment in early childhood.
Claire A. Wilson, Gillian Santorelli, Emily Simonoff, Louise M. Howard, Khalida Ismail, Rebecca M. Reynolds   +5 more
wiley   +1 more source