Genetic differentiation of the Western Capercaillie highlights the importance of South-eastern Europe for understanding the species phylogeography. [PDF]
Bajc M +9 more
europepmc +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Intralingual Variation in Acceptability Judgments and Production: Three Case Studies in Russian Grammar. [PDF]
Gerasimova A, Lyutikova E.
europepmc +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Patient Reported Indicator Surveys (Paris): Methodological Considerations of a Field Trial in Slovenia. [PDF]
Ambrož M +3 more
europepmc +1 more source
Computed Tomographic Perfusion Imaging for the Prediction of Response and Survival to Transarterial Chemoembolization of Hepatocellular Carcinoma. [PDF]
Popovic P +5 more
europepmc +1 more source
Taxonomy of Dianthus (Caryophyllaceae) - overall phylogenetic relationships and assessment of species diversity based on a first comprehensive checklist of the genus. [PDF]
Fassou G +5 more
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Datenschutz bei Pervasive Computing im Gesundheitswesen
Johann Čas
doaj +1 more source

