Results 81 to 90 of about 161,702 (247)

Snert: Ritual-liturgical measurements and recipes for social capital

Verbum et Ecclesia, 2010
The questions of how social capital is measured and how it is generated have received ample attention in recent years. This article is an attempt at making a modest contribution towards addressing these issues and specifically also as a contribution from
Cas Wepener
doaj   +1 more source

GridEngine Reporting Tool [PDF]

, 2016
Cílem této práce je sestavit nástroj, který bude odrážet využití výpočetního clusteru postaveného na technologii Grid Engine. Data jsou zpracována pomocí PHP a Shell skriptů a následně uložena do MySQL, či RRD databází. V práci byl vytvořen systém, který
Rožek, František
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Do We Have the Spark? [PDF]

Zdr Varst, 2022
Rupel VP, Marušič D.
europepmc   +1 more source

Algorithm for Virtual Waiting Room Handling [PDF]

, 2016
Tato práce se věnuje problematice virtuálních čekáren, informuje o aktuálně dostupných produktech a programovacích prostředcích, hodnotí je a nabízí řešení nedostatků zjištěných v současném stavu.
Mrázek, Patrik
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Application of the Robai 1500 Robotics Arm [PDF]

, 2016
Import 02/11/2016Diplomová práce se zabývá tvorbou ovládací aplikace pro robotické rameno Robai Gamma 1500. V úvodu práce je popsané robotické rameno. V práci je pospaná ovládací aplikace dodávaná výrobcem.
Vavřík, Pavel
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Production technology of parts [PDF]

, 2015
Bakalářská práce se zaměřuje na návrh technologií a výrobu součásti bimetalový válec ve firmě Bernex Bimetallic s.r.o. Po úvodu se zaměřuje na teoretický rozbor strojního obrábění, poté se věnuje technologičnosti součástky Bimetalový válec.
Bartl, Lukáš
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source