Results 81 to 90 of about 164,635 (296)

Distribution Pipe of Pelton Turbine [PDF]

open access: yes, 2008
Tato bakalářská práce popisuje problematiku návrhu okružního potrubí Peltonovy turbíny a uvádí způsoby zjednodušení realizace tohoto potrubí. Srovnávána je zde varianta potrubí vyrobeného ze svařovaných plechů, s variantou z bezešvých trubek spojených ...
Halabrin, Robin
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Routing Algorithms in MANET Networks [PDF]

open access: yes, 2019
Tato bakalářská práce je zaměřena na problematiku sítí MANET, VANET a analýzu směrovacích protokolů. Pozornost budeme věnovat především DSR, OLSR a AODV protokolům.
Ščurek, Petr
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Rationalisation of drilling technology [PDF]

open access: yes, 2014
Diplomová práce je zaměřena na racionalizaci technologie vrtání děr v ložiskových kroužcích určených pro větrné elektrárny. Práce obsahuje přehled vrtacích nástrojů, rozbor stávajícího stavu a návrh racionalizačních opatření. Racionalizační opatření jsou
Rozum, Josef
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Production of Parts into the Injection Mold [PDF]

open access: yes, 2014
Tento projekt spracováva technológiu výroby súčasti do zostavy vstrekovacej formy v daných podmienkach spoločnosti ROTEK s.r.o. so zameraním na využitie elektroerozívneho obrábania.
Pilarčík, Edmund
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

SPÔSOBY REPREZENTÁCIE RIEŠENIA ÚLOHY KOORDINÁCIE CESTOVNÝCH PORIADKOV GENETICKÝMI ALGORITMAMI

open access: yesPerner’s Contacts, 2009
Článok je zameraný na spôsoby reprezentácie úlohy zostavovania a optimalizácie cestovných poriadkov pre mestskú hromadnú dopravu v rámci prestupného uzla.
Gabriel Fedorko   +2 more
doaj  

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