Results 141 to 150 of about 21,037 (220)

Philadelphia chromosome‐positive acute lymphoblastic leukaemia in children and adolescents: A changing treatment landscape and a methodological challenge

British Journal of Haematology, EarlyView.
Adriana Balduzzi, Maria Grazia Valsecchi, Thai Hoa Tran, Jan Zuna, Veronica Leoni, Gunnar Cario, Grazia Fazio, Virginie Gandemer, Sarah K. Tasian, Inge M. van der Sluis, Nicolò Peccatori, Rosanna Parasole, Stefania Monterisi, Mignon L. Loh, Meenakshi Devidas, Stephen P. Hunger, John A. Kairalla, Paola De Lorenzo, Lewis B. Silverman, Andrea Biondi   +19 more
wiley   +1 more source

Lock, relax, load, and shoot: a molecular perspective on Nedd4 regulation

The FEBS Journal, EarlyView.
Structural basis of inactive and active states of the Nedd4 HECT E3 ligase subfamily, following a ‘lock, relax, load, and shoot’ mechanism. In the locked, autoinhibited state, intramolecular domain interactions restrain the HECT domain. Relaxation releases these restraints, allowing loading of ubiquitin onto the catalytic cysteine, followed by the ...
Masa Janosev, Tomas Obsil, Veronika Obsilova   +2 more
wiley   +1 more source

Vztah k místu: nonkognitivní učení žáků 1. stupně

Envigogika
Místo jako geografický fenomén se do výuky propisuje mnohem dříve, než se žák ve školním prostředí setká se zeměpisem jako samostatným předmětem. Od narození vnímaný a rozvíjený vztah k místu se ukazuje jako důležitá součást přírodovědné gramotnosti a ...
Jan Musil
doaj   +1 more source

Vybrané problémy česko-polské terminologie sportu

Slavica Iuvenum XXII. Sborník příspěvků z mezinárodní vědecké konference Slavica Iuvenum 2021, 2021
Jana Pikulová
semanticscholar   +1 more source

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

The FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek, Miroslava Vosahlikova, Zsofia Kutil, Zora Novakova, Julia Kudlacova, Ruzena Tuckova, Marat Meleshin, Barbora Havlinova, Pavlina Jaklova, Jana Ptackova, Cordelia Schiene‐Fischer, Mike Schutkowski, Cyril Barinka   +12 more
wiley   +1 more source

"My sme ľud, kto ste vy?" Storočie populizmu v (Česko)Slovensku

, 2021
Ivana Piterová, Lucia Heldáková, Klara Kohoutová   +2 more
semanticscholar   +1 more source

Disentangling the Drivers of a Piscivorous Intra‐Annual Cohort and the Contributions of Three Cohorts to Early‐Year Class Strength in Pikeperch (Sander lucioperca)

Fisheries Management and Ecology, EarlyView.
ABSTRACT Using pikeperch (Sander lucioperca) as a model species, we investigated the factors influencing fluctuations in the abundance of piscivorous intra‐annual cohorts and assessed the role of three distinct cohorts: extremely small (ES), ordinary (or mid‐sized) fingerlings, and piscivorous in shaping year‐class strength.
Million Tesfaye, Tomáš Jůza, Marek Šmejkal, Katerina Soukalová, Daniel Bartoň, Petr Blabolil, Martin Čech, Josef Hejzlar, Marie Prchalová, Milan Muška, Michal Tušer, Luboš Kočvara, Zuzana Sajdlová, Vladislav Draštík, Carlos Martinez, Karlos Ribeiro de Moraes, Milan Říha, Mojmír Vašek, Radka Symonová, Marek Brabec, Jan Kubečka, Allan T. Souza   +21 more
wiley   +1 more source

Engaging With Policymakers and Practitioners to Implement Restorative Justice in Europe: Lessons From 10 Countries in Restorative Justice: Strategies for Change

The Howard Journal of Crime and Justice, EarlyView.
ABSTRACT Research suggests that enabling greater participation in restorative justice can lead to strong social, health and economic benefits for people who commit offences, victims, communities and states. Yet, restorative justice remains partially implemented in Europe and many people cannot easily access services in practice, even in countries with ...
Ian D. Marder, Ruairí Weiner, Anna Matczak, Steve Kirkwood, Gert Jan Slump   +4 more
wiley   +1 more source

Urban birds' detectability is affected by inter‐ and intraspecific variation in shyness

Ibis, EarlyView.
Detection probabilities differ between bird species as a function of their life history and ecological and behavioural traits, inevitably introducing bias in their abundance and occupancy estimates. However, the effects of behavioural traits such as species shyness and vigilance on detectability remain poorly understood.
Peter Mikula, Federico Morelli, Annette Menzel, Piotr Tryjanowski   +3 more
wiley   +1 more source

Heterogeneous Agents Model with the Worst Out Algorithm [PDF]

Heterogeneous agents' model with the stochastic beliefs formation is considered. Fundamentalists rely on their model employing fundamental information basis to forecast the next price period.
Lukáš Vácha, Miloslav Vošvrda
core   +1 more source