Results 191 to 200 of about 21,037 (220)
Soluble SORL1 in cerebrospinal fluid as a marker for functional impact of rare SORL1 variants
Abstract INTRODUCTION The sortilin‐related receptor (SORL1) directs APP and Aβ trafficking within the retromer pathway. Cleavage at the cell surface releases soluble SORL1 (sSORL1) into cerebrospinal fluid (CSF). We examined whether CSF‐sSORL1 can serve as an in vivo marker of genetically impaired SORL1.
Matthijs W. J. de Waal +24 more
wiley +1 more source
Obligatory brood parasitism in the Lake Tanganyika cuckoo catfish requires rapid reproductive readiness to exploit unpredictable host spawning. Our experiments showed that males are almost continuously ready to reproduce, while females ovulate about once a week, with social interactions enhancing gamete maturation in both sexes.
Holger Zimmermann +5 more
wiley +1 more source
Dušan Segeš – Maroš Hertel – Valerián Bystrický (eds.): Slovensko a slovenská otázka v poľských a maďarských diplomatických dokumentoch v rokoch 1938–1939. [PDF]
Mitrovits, Miklós
core
All‐Fiber Microsensor of Polarization at Single‐Photon Level Aided by Deep Learning
Introducing a polarization sensor using scattering in a short optical fiber and deep learning. The breakthrough lies in sparse sampling of the scattered light and single‐photon sensitivity. The all‐fiber sensor achieves unprecedented accuracy, speed, resolution, and stability.
Martin Bielak +2 more
wiley +1 more source
Hyaluronan degradation in Bacteroides cannot be reliably predicted from canonical PL8/GH88 enzymes alone. Experimental validation reveals coordinated induction of noncanonical accessory proteins (BT4410/BT4411), highlighting pathway plasticity and context‐dependent glycosaminoglycan utilization. ABSTRACT The ability of gut microbes to degrade host‐ and
Martin Sindelar +6 more
wiley +1 more source
Beyond contacts: The important role of the support region in protein complex assembly
Abstract Protein–protein interactions (PPIs) are fundamental to nearly all cellular processes; however, elucidating the principles governing protein association into complexes remains a significant challenge. Previous studies have shown that protein–protein interfaces can be partitioned into distinct regions—core, rim, and support—that differ in ...
Tom Miclot, Stepan Timr
wiley +1 more source
[Konečný, Milan. Česko-novořecký slovník]
Markéta Kulhánková
doaj +2 more sources
Is UWLS Really Better for Medical Research?
ABSTRACT This study evaluates the performance of the Unrestricted Weighted Least Squares (UWLS) estimator in meta‐analyses of medical research. Using a large‐scale simulation approach, it addresses the limitations of model selection criteria in small‐sample contexts.
Sanghyun Hong, W. Robert Reed
wiley +1 more source
ABSTRACT Objective To test the non‐inferiority of extended abdominopelvic ultrasound examination compared with contrast‐enhanced computed tomography (CT) and whole‐body diffusion‐weighted magnetic resonance imaging (WB‐DWI/MRI) in discriminating preoperatively between resectable and non‐resectable disease based on the European Society for Medical ...
D. Fischerova +26 more
wiley +1 more source
Contrasting drought responses in two grassland plant–microbe systems under climate change
By contrasting two plant strategies across a soil‐moisture gradient under warming and elevated CO2, this study shows how drought and climate jointly shape plant performance and associated microbiomes. The stress‐tolerant Festuca rubra responds through trait plasticity and flexible bacterial communities, whereas the competitive Lolium perenne relies ...
Gang Yang +4 more
wiley +1 more source

