Results 61 to 66 of about 69 (66)

Thermostable Bioluminescent Intercalating Dyes for Real‐Time, Integrated Nucleic Acid Amplification and Detection

open access: yesAngewandte Chemie, Volume 138, Issue 29, 13 July 2026.
We present a bioluminescent diagnostic platform that integrates DNA amplification and detection in a single step. The engineering of thermostable luciferase‐intercalating dye conjugates and controlled release of caged luciferin substrates enable real‐time, detection of attomolar concentrations of viral DNA within 30 min.
Yosta de Stigter   +8 more
wiley   +2 more sources

Metoprolol Population Pharmacokinetics in Older Chinese Patients With CKM Syndrome: Joint Effects of rs1065852 and CKM2S2‐BAG Score on Clearance

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
PopPK modeling and simulation workflow for metoprolol in older Chinese patients with CKM syndrome. ABSTRACT Older adults are vulnerable to adverse drug reactions due to multimorbidity, frailty and polypharmacy. In those with cardiovascular‐kidney‐metabolic (CKM) syndrome, CKM‐related multi‐organ burden may further alter drug disposition and elevate ...
Haodi Chai   +8 more
wiley   +1 more source

Does faster aspart improve time in range in children with type 1 diabetes with glycaemia close to target on insulin pump therapy?

open access: yesDiabetic Medicine, Volume 43, Issue 8, August 2026.
Abstract Aims To evaluate whether faster insulin aspart (FIA) improves time in range (TIR) compared with standard insulin aspart (SIA) in children and adolescents with type 1 diabetes achieving glycaemia close to target treated with continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring (CGM).
Kowalczyk‐Korcz Emilia   +3 more
wiley   +1 more source

Using Eye Lens Stable Isotopes to Identify the Rearing Origin of Fall Age‐0 Walleye (Sander vitreus)

open access: yesFisheries Management and Ecology, Volume 33, Issue 4, Page 775-783, August 2026.
ABSTRACT Isotope values in fish eye lenses may be useful in differentiating rearing origins. We compared eye lens isotopic values of fall fingerling age‐0 walleye (Sander vitreus) reared in a hatchery pond, a recirculating aquaculture system (RAS), and a natural lake. Using 10 fish per rearing source, we delaminated layers from one eye lens per fish to
Justin M. Sturtz   +5 more
wiley   +1 more source

Light Element Exsolution in Fe‐Si‐C‐(H) System: A Mechanism for Powering Mercury's Early Core Dynamo

open access: yesGeophysical Research Letters, Volume 53, Issue 14, 28 July 2026.
Abstract Mercury is one of the few terrestrial planets in the solar system with a magnetic field, yet the energy source to power its core dynamo remains unclear to date. Si, C, and possibly H are the top candidate light elements for its liquid core. Here, we showed experimentally that Si, C, and H in Fe‐Si‐C and Fe‐Si‐C‐H liquids share a simultaneous ...
Yuanjing Li   +5 more
wiley   +1 more source

Does Zonal Wave 3 Affect Total Antarctic Sea Ice Area?

open access: yesGeophysical Research Letters, Volume 53, Issue 14, 28 July 2026.
Abstract While it is well‐established that Zonal Wave Three (ZW3) can drive regional expansion or contraction of Antarctic sea ice, it is unclear whether it has an effect on circumpolar total sea ice area (SIA). Here, we provide evidence to challenge previous studies' attribution of large overall Antarctic SIA decreases to ZW3.
Michael D. Eabry   +2 more
wiley   +1 more source

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