Results 91 to 100 of about 7,491 (112)

Population Pharmacokinetics and Dose De‐Escalation Regimens of Subcutaneous Vedolizumab in Inflammatory Bowel Disease

open access: yesJCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Background Vedolizumab is a therapeutic antibody approved for the treatment of Crohn's disease and ulcerative colitis. The population pharmacokinetics (popPK) of intravenous (IV) administered vedolizumab have been described, but remain to be defined for subcutaneous (SC) administration.
S. I. Anjie   +5 more
wiley   +1 more source

Integrating habitat suitability, socioeconomics, and infrastructure to assess global biological invasion risk under climate change: A case study of the rice stem borer, Chilo suppressalis

open access: yesPest Management Science, Volume 82, Issue 9, Page 9068-9086, September 2026.
We developed an invasion risk index framework that integrates socioeconomic and environmental data using an entropy‐weighting method. The case study highlights the need for region‐specific biosecurity measures for Chilo suppressalis. Abstract BACKGROUND Biological invasion risk is a multifaceted concept that, according to the Food and Agriculture ...
Jinsol Hong   +11 more
wiley   +1 more source

De Stupro: First Insights on Rape and Its Prosecution in Maltese Courts (1701–10)

open access: yesJournal for Eighteenth-Century Studies, Volume 49, Issue 3, Page 265-286, September 2026.
Abstract This article constitutes a first in‐depth investigation of rape and the prosecution of this crime in early eighteenth‐century Malta. The research, which is based on sixteen rape accusations claimed at the secular courts in Malta between 1701 and 1710, has analysed cases categorized as ‘simple rape’, ‘violent rape’ and rape committed under the ...
Vanessa Buhagiar
wiley   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan   +3 more
wiley   +1 more source

The Manifold Impacts of Management Research

open access: yesJournal of Management Studies, Volume 63, Issue 6, Page 2831-2860, September 2026.
Abstract Management scholarship's apparent lack of impact is a misconception based on the presumption that impact involves a direct and visible influence of papers or research projects on management practice. Theory‐building impacts management practice in diverse, sometimes indirect and unnoticed, manifold ways.
Matthias Wenzel   +3 more
wiley   +1 more source

İbnü'r-Râvendî'nin Şiî Düşüncedeki Yeri

open access: yesTurkish Journal of Shiite Studies, 2019
Çalkantılı olayların görüldüğü ve fikri açıdan gelişmelerin kaydedildiği hicri 3. asırda Bağdat'ta yaşayan İbnü'r-Râvendî'nin Bağdat'ta bulunduğu dönemde, Abbasi Devleti'nde Me'mûn, Mu'tasım, Vâsık ve Mütevekkil olmak üzere dört halife değişmiştir.
Rumeysa Balcı
doaj  

Optimized SPE‐HPLC‐FLD Method for the Simultaneous Determination of Olaparib, Propranolol, and Furosemide in Human Urine

open access: yesBiomedical Chromatography, Volume 40, Issue 8, August 2026.
ABSTRACT Olaparib belongs to the PARP inhibitors and is widely used as an anticancer drug. Due to frequent side effects, it is usually co‐administered with an antihypertensive, such as propranolol and/or an antidiuretic, such as furosemide. In this study, a highly sensitive HPLC‐FLD method was developed for the simultaneous determination of the three ...
Georgios Kamaris   +2 more
wiley   +1 more source

Saudi Medical Students' Perceptions and Attitudes of Integrating Generative Artificial Intelligence Integration in Medical Education: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Generative Artificial Intelligence (GenAI) has catalyzed a transformation in medical education. Understanding learners' perceptions is essential to guide their responsible integration into curricula. Methods A cross‐sectional survey was administered to 1039 undergraduate medical students across Saudi Arabia.
Fadi Aljamaan   +18 more
wiley   +1 more source

Mitochondria Dictate Progressive Versus Bimodal Aging of the Mammary Gland

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
Breast cancer shows a bimodal age distribution with a peak at 45 and higher peak at 65. Using mice with different mitochondrial genomes, we show progressive and bimodal patterns of aging of the mammary gland with distinct pro‐tumorigenic age windows. This finding may shed light on the bimodal distribution in humans.
Edmund Charles Jenkins   +6 more
wiley   +1 more source

Astigmatic changes after Descemet membrane endothelial keratoplasty (DMEK) in decompensated penetrating keratoplasty grafts

open access: yesActa Ophthalmologica, Volume 104, Issue 5, Page e516-e529, August 2026.
Abstract Purpose To evaluate the surgery‐induced changes of astigmatism after Descemet membrane endothelial keratoplasty (DMEK) in eyes with failed previous penetrating keratoplasty (PK). Design Retrospective, interventional cohort study based on prospective DMEK database.
Florian Thomas Steinberg   +6 more
wiley   +1 more source

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