Results 171 to 180 of about 7,637 (185)
Novel methoxyphenol‐1,2,3‐triazole hybrids were synthesized as multifunctional leads. Compound 5e exhibited potent PC3 cytotoxicity (IC50: 3.57 μM), while 5c showed superior AChE inhibition (IC50: 1.44 μM) and high selectivity (SI: 6.22). DFT and docking studies confirmed their dual‐targeting potential, providing a robust scaffold for Alzheimer's and ...
Sultan Onur +2 more
wiley +1 more source
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs +7 more
wiley +1 more source
Shaping future forests: how can ecophysiology support climate‐smart forest management?
Summary Climate change, particularly the associated increase in extreme events and disturbances, threatens the numerous environmental, social, and economic benefits that forests provide, both locally and globally. Heat and drought pose significant risks to forest ecosystems; the anticipated future climate is expected to exacerbate this trend ...
Arthur Gessler +18 more
wiley +1 more source
ABSTRACT Objectives Understanding suicide risk remains a global health challenge, yet one under‐researched avenue involves examining internalized cognitions related to suicide. This study examined cognitive reactivity and ego depletion in relation to participants' suicide history and the frequency, duration, and intensity of suicidal ideation.
Yawen Zheng +3 more
wiley +1 more source
Sorulu-Cevaplı Şia İtikadı 12 İmamcı İmamiyye Şiasının İtikadı
ORAL, MURAT
core +1 more source

