Results 31 to 40 of about 43,582 (236)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Delo in delovni pogoji reševalcev iz vode
ŠportPrispevek obravnava delo in delovne pogoje reševalcev iz vode na bazenskih kopališčih v Sloveniji. Raziskava je bila izvedena na vzorcu 70 reševalcev in je proučevala skladnost delovnih pogojev z zakonodajo, obremenjenost z dodatnimi nalogami ...
Hana Lukman, Dorica Šajber
doaj +1 more source
Neformalno pridobivanje znanja tujega jezika
AS: Andragoška Spoznanja, 2010 Izobraževanje je kompleksna struktura različnih procesov, v katerih se dinamično prepletata tako formalno kot neformalno izobraževanje. Namen raziskave je bil ugotoviti, kakšen vpliv imajo različne oblike neformalnega izobraževanja na uspeh učenja ...
Katarina Bizjak
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Priljubljenost šolskega predmeta šport med učenci 3. razredov in njihovo mnenje o njegovi pomembnosti za življenje [PDF]
, 2015 Na vzorcu 245 učencev 3. razredov različnih osnovnih šol gorenjske in ljubljanske regije smo ugotavljali priljubljenost šolskega predmeta šport. Zanimalo nas je tudi, kako pomemben se jim ta predmet zdi za življenje.
Petrušič, Tanja
core
Substances in the life of children 8–10 years old [PDF]
, 2014 Miklánková Ludmila, Reich Petr, Klimešová Iva, Rechtik Zdeněk. Substances in the life of children 8–10 years old. Journal of Health Sciences. 2014;4(13):85-94. ISSN 1429-9623 / 2300-665X.
Petr Reich +7 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Šport v rimski Sloveniji [PDF]
Roman sports originated as religious and mortuary rituals. Chariot races, potentially the oldest discipline, were held to ensure bountiful harvests, while gladiatorial contests were part of funerary festivals.
Stemberger Flegar, Kaja
core +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source