Results 61 to 70 of about 358,589 (291)
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Zaposlovanje vrhunskih športnikov v javni upravi na preizkušnji
Central European Public Administration Review, 2011 Med vsebine ter strokovne in razvojne naloge, ki predstavljajo obstoječo podporo države športnikom sodi tudi zaposlovanje vrhunskih športnikov v državni upravi.
Darko Repenšek
doaj +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Differences in athropological features of children in preschool institutions with regard to educational groups [PDF]
, 2018 Istraživanje je provedeno na 30 djece predškolske dobi. Ukupan uzorak podijeljen je u dva subuzorka, prvi je činilo 15 djece koja pohađaju sportski program u trajanju od 5 sati tjedno, a drugi subuzorak činilo je 15 djece koja pohađaju redoviti program ...
Varjačić, Nikolina
core +1 more source
Journal of athletic training, 2019 OBJECTIVE To evaluate sex differences in incidence rates (IRs) of anterior cruciate ligament (ACL) injury by sport type (collision, contact, limited contact, and noncontact). DATA SOURCES A systematic review was performed using the electronic databases
Alicia M. Montalvo +12 more
semanticscholar +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Zasnova športne infrastrukture v prostoru [PDF]
Urbani Izziv, 1998 Skladen razvoj športa obravnava razvoj športnih središč, objektov in vadišč predvsem v grajenem okolju. Njihov temeljni namen je zadovoljitev potreb vrhunskega in kakovostnega športa, športne rekreacije in športne vzgoje v prostoru.
Boris Leskovec
doaj