Results 91 to 100 of about 88,228 (240)

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells

Advanced Healthcare Materials, EarlyView.
Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina, Jane Sun, Seen Ling Sim, Imaan A. Ahmed, Fernando Souza‐Fonesca‐Guimaraes, Ernst J. Wolvetang, Jason Brown, Snehlata Kumari, Kiarash Khosrotehrani, Abbas Shafiee   +9 more
wiley   +1 more source

Norbornene Homopolymerization Limits Cell Spreading in Thiol–Ene Photoclick Hydrogels

Advanced Healthcare Materials, EarlyView.
Thiol–norbornene click reactions are often used in the development of cell‐permissive 3D hydrogels. However, ene–ene crosslinks in other thiol–ene systems are known to limit permissivity. This study demonstrates the negative effects of norbornene homopolymerization on 3D cell spreading and circumvents the issue by modulating polymer degree of ...
James L. Gentry, Steven R. Caliari
wiley   +1 more source

Engineering Volumetric Tissue Analogs via Assembly of Endothelial Cell‐Covered Spheroidal Microtissues

Advanced Healthcare Materials, EarlyView.
An engineering strategy to fabricate highly vascularized volumetric tissues with capillary networks is developed. Endothelial cell‐covered spheroidal microtissues with high structural integrity are efficiently produced using bioprinting technology. These spheroidal microtissues are then assembled and cultured under perfusion conditions, resulting in ...
Hyeongkwon Oh, Jae‐Hun Kim, Sunwoo Lee, Jin‐Hyung Shim, Won‐Soo Yun, Songwan Jin   +5 more
wiley   +1 more source

The anti-adjacency matrix of a graph: Eccentricity matrix

Discrete Applied Mathematics, 2018
Jianfeng Wang, Mei Lu, Francesco Belardo, M. Randic   +3 more
semanticscholar   +1 more source

Biomimetic Mineralization of Keratin Scaffolds for Enamel Regeneration

Advanced Healthcare Materials, EarlyView.
Keratin‐based films guide biomimetic enamel remineralization by promoting organized hydroxyapatite growth under physiological conditions. Advanced biophysical characterization confirms keratin's structural adaptability and mineral ions‐binding affinity, supporting mineral nucleation and hierarchical crystal assembly. This study establishes keratin as a
Sara Gamea, Elham Radvar, Dimitra Athanasiadou, Ryan Lee Chan, Giacomo De Sero, Ecaterina Ware, Sunie Kundi, Avir Patel, Shwan Horamee, Shuaib Hadadi, Mads Carlsen, Leanne Allison, Roland Fleck, Ka Lung Andrew Chan, Avijit Banerjee, Nicola Pugno, Marianne Liebi, Paul T Sharpe, Karina Carneiro, Sherif Elsharkawy   +19 more
wiley   +1 more source

A Modular Perfusion Bioreactor Platform for Simulating Bone Regeneration and Fracture Healing: Integrating Mechanical Loading and Dual Perfusion for Advanced In Vitro Models

Advanced Healthcare Materials, EarlyView.
A modular bioreactor platform was developed in order to replicate bone homeostasis and pathology, thereby integrating mechanical loading, dynamic perfusion, and a 3D‐printed microfluidic chamber. With precise control of environmental parameters and dual perfusion for composite tissue models, the system enhances physiological relevance for studying bone
Moritz Pfeiffenberger, Alexandra Damerau, Johannes Plank, Adel Ahmed, Mario Thiele, Jan Saam, Paula Hoff, Timo Gaber, Frank Buttgereit   +8 more
wiley   +1 more source

Stable brain PET metabolic networks using a multiple sampling scheme. [PDF]

Netw Neurosci
Schu G, Limberger C, Brum WS, De Bastiani MA, Rodrigues YE, de Azeredo JC, Pascoal TA, Benedet AL, Mathotaarachchi S, Rosa-Neto P, Almeida J, de Paula Faria D, de Souza Duran FL, Buchpiguel CA, Coutinho AM, Busatto GF, Zimmer ER, Alzheimer’s Disease Neuroimaging Initiative.   +17 more
europepmc   +1 more source

Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review

Advanced Healthcare Materials, EarlyView.
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli, Seshasai Srinivasan, Amin Reza Rajabzadeh   +2 more
wiley   +1 more source

Prediction of Standard Combustion Enthalpy of Organic Compounds Combining Machine Learning and Chemical Graph Theory: A Strategy. [PDF]

ACS Omega
Saviñon-Flores F, Arzola-Flores JA, García-Castro MA, Díaz-Sánchez F, Vidal Robles E, Maruri Valderrabano FA.   +5 more
europepmc   +1 more source