Results 121 to 130 of about 137,715 (267)

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

The Maximum Order of Reduced Square(0, 1)-Matrices with a Given Rank

We look for the maximum order of a square (0, 1)-matrix A with a fixed rank r, provided A has no repeated rows or columns. If A is the adjacency matrix of a graph, Kotlov and Lovász [J. Graph Theory 23, 1996] proved that the maximum order equals Θ(2r/2).
Peeters, M.J.P., Haemers, W.H.
core  

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

Advanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach, Reza Kowsari‐Esfahan, Emilia Reszczyńska, Philippe Nghe, Matthias Nees   +4 more
wiley   +1 more source

Adjacency graph based matrix representations and operations of metamorphic mechanisms

, 2014
Metamorphic mechanisms are widely studied and applied in theory and practice because of their characteristics of variable topological structures. The adjacency matrix is used in representation and operation of link changes.
Wei, Shi Min, Dai, Jian Sheng, Li, Duan Ling, Bai, Guo Chao, Liao, Qi Zheng   +4 more
core   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

The $k$-adjacency operators and adjacency Jacobi matrix on distance-regular graphs

We deal in this work with a class of graphs, namely, the class of distance-regular graphs, in which on the basis of $k$-adjacency operators, the adjacency operator $A$ of a distance-regular graph is identified as a Jacobi matrix.
Rios-Cangas, Josué I.
core   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

THE ADJACENCY MATRIX AND THE DISCRETE LAPLACIAN ACTING ON FORMS

, 2015
We study the relationship between the adjacency matrix and the discrete Laplacian acting on 1-forms. We also prove that if the adjacency matrix is bounded from below it is not necessarily essentially self-adjoint.
Baloudi, Hatem, Golenia, Sylvain, Jeribi, Aref   +2 more
core   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Clustering Based on Eigenvectors of the Adjacency Matrix

, 2018
The paper presents a novel spectral algorithm EVSA (eigenvector structure analysis), which uses eigenvalues and eigenvectors of the adjacency matrix in order to discover clusters.
Wierzchoń, S. T., Lucińska Małgorzata, Małgorzata Lucińska, Wierzchoń Sławomir T., Sławomir T. Wierzchoń, Lucińska, M.   +5 more
core   +1 more source