Results 21 to 30 of about 1,349 (139)

One-Pot Synthesis and Antimicrobial Activity of Novel α-Aminophosphonates Using TMG [PDF]

E-Journal of Chemistry, 2011
α-Aminophosphonates (4a-j) were synthesized in one-pot simultaneous reaction of 4-bromo-3-methyl benzenamine (1), dimethylphosphite (3) and different aromatic aldehydes (2a-j) by Kabachnik-Fields reaction in the presence of tetramethylguanidine (TMG) (10
B. Siva Kumar, Y. Haranadha Reddy, C. Radha Rani, G. Chnadra Sekhar Reddy   +3 more
doaj   +3 more sources

Efficient synthesis of α-aminophosphonates using magnetically retrievable ionic nanocatalysts under ultrasound acceleration [PDF]

Scientific Reports
Magnetic supported ionic liquids are a unique subclass of ionic liquids that possess the ability to respond to external magnetic fields, combining the advantageous properties of traditional ILs with this magnetic responsiveness.
Farzaneh Saboury, Najmedin Azizi, Zohreh Mirjafari, Mohammad Mahmoudi Hashemi   +3 more
doaj   +2 more sources

Ru-Catalyzed Asymmetric Transfer Hydrogenation of α-iminophosphonates: A Novel Synthetic Approach for Valuable Chiral α-Aminophosphonates. [PDF]

Chemistry
This study reports the first Ru‐catalyzed ATH of α‐iminophosphonates, enabling the efficient synthesis of chiral α‐aminophosphonates. Both acyclic and cyclic substrates are converted in high yields (up to 97%) with excellent enantioselectivities (up to >99:1), offering a practical alternative to conventional AH for accessing phosphorus‐containing ...
Plouard P, Borrel L, Butin PO, Muller P, Cherpitel R, Loiseau S, Clarion L, Virieux D, Ayad T.   +8 more
europepmc   +2 more sources

Catalyst-Free Cross-Dehydrogenative Coupling Strategy Using Air as an Oxidant: Synthesis of α‑Aminophosphonates [PDF]

ACS Omega, 2017
Jayaraman Dhineshkumar, Prasanjit Samaddar, Kandikere Ramaiah Prabhu   +2 more
doaj   +2 more sources

Asymmetric Transfer Hydrogenation as a Key Step in the Synthesis of the Phosphonic Acid Analogs of Aminocarboxylic Acids. [PDF]

Chemistry, 2023
The asymmetric transfer hydrogenation (ATH) of 17 diisopropyl α‐oxophosphonates was accomplished by using a commercially available Noyori‐type catalyst. The highly enantioenriched products (ee >98 % in all cases but one) were further converted to the phosphonic acid analogs of 15 aminocarboxylic acids.
Dinhof T, Kalina T, Stanković T, Braunsteiner K, Rohrbach P, Turhan E, Gradwohl A, Königshofer A, Horak J, Pallitsch K.   +9 more
europepmc   +2 more sources

Cytotoxic Activity of α-Aminophosphonic Derivatives Coming from the Tandem Kabachnik–Fields Reaction and Acylation

Pharmaceuticals, 2023
Encouraged by the significant cytotoxic activity of simple α-aminophosphonates, a molecular library comprising phosphonoylmethyl- and phosphinoylmethyl-α-aminophosphonates, a tris derivative, and N-acylated species was established.
Petra R. Varga, Rita Oláhné Szabó, György Dormán, Szilvia Bősze, György Keglevich   +4 more
doaj   +1 more source

New Cytotoxic Derivatives by the Phosphorylation and Phosphinoylation of Diethyl α-Amino-α-Aryl-Methylphosphonates. [PDF]

Chemistry
In order to make available potentionally bioactive new α‐aminophosphonic derivatives, diethyl α‐amino‐α‐aryl‐methylphosphonates were phosphorylated, phosphinoylated and thiophosphinoylated with the corresponding P‐chloride. The effect of a P=O to P=S modification was evaluated by single crystal X‐ray cristallography.
Bircher M, Karaghiosoff K, Czugler M, Takács A, Kőhidai L, Drahos L, Keglevich G.   +6 more
europepmc   +2 more sources

Michael addition of P-nucleophiles to azoalkenes provides simple access to phosphine oxides bearing an alkylhydrazone moiety

Frontiers in Chemistry, 2023
β-Hydrazonophosphine oxides are precursors of useful organophosphorus compounds, including phosphorylated N-heterocycles, α-aminophosphonates, and vinylphosphonates.
Alexandr O. Kokuev, Alexey Yu. Sukhorukov   +1 more
doaj   +1 more source

Microwave-assisted synthesis of α-aminophosphonates with sterically demanding α-aryl substituents [PDF]

, 2020
A series of N-benzhydryl protected α-aminophosphonates with α-phenyl, α-(1-naphtyl), α-(9-anthryl) or α-(1-pyrenyl) substituents was synthesized by the Kabachnik–Fields condensation of diphenylmethylamine (benzhydrylamine), the corresponding aryl ...
Bálint, Erika, Czugler, Mátyás, Hudson, Harry R., Karaghiosoff, Konstantin, Keglevich, György, Tajti, Ádám   +5 more
core   +1 more source

Development of titanium oxide-bound-α-aminophosphonate nanocomposite for adsorptive removal of lead and copper from aqueous solution

Water Resources and Industry, 2020
A novel nanocomposite (N–TiO2-α-Am.Ph) was designed by surface functionalization of nano titanium oxide (N–TiO2) with α-aminophosphonates (α-Am.Ph). A study was aimed to explore and investigate the uptake properties of (N–TiO2-α-Am.Ph) for divalent Pb/Cu
Mohamed E. Mahmoud, Shymaa E. Adel, Ibrahim E.T. ElSayed   +2 more
doaj   +1 more source