Results 61 to 70 of about 1,349 (139)

Biomolekuláris felismerésre képes makrociklusos receptorok szintézise = Synthesis of macrocyclic receptors capable of biomolecular recognition [PDF]

open access: yes, 2013
1. Kalix-és binaftokorona éterek szintézise és alkalmazásuk 1.1. Kalix[6]arén Mitsunobu ciklizációját tanulmányoztuk 1,6-és 1,8-oktándiollal és a termékek konformációját meghatároztuk 1.2.
Bitter, István   +2 more
core  

Design, Synthesis, Biological Evaluation and Molecular Docking Studies of New Thiazolidinone Derivatives as NNRTIs and SARS‐CoV‐2 Main Protease Inhibitors

open access: yesChemistry &Biodiversity, Volume 21, Issue 12, December 2024.
Abstract HIV‐1 remains a major health problem worldwide since the virus has developed drug‐resistant strains, so, the need for novel agents is urgent. The protein reverse transcriptase plays fundamental role in the viruses’ replication cycle. FDA approved Delavirdine bearing a sulfonamide moiety, while thiazolidinone has demonstrated significant anti ...
Maria Fesatidou   +2 more
wiley   +1 more source

The preparation of α -aminopropane phosphonic acid via the catalyzed hydrogenation of dimethyl or diethyl α-hydroxy-imino-propanephosphonate [PDF]

open access: yes, 2010
The use of catalytic hydrogenation for the conversion of α -hydroxyiminophosphonates into α -aminophosphonates (and hence α -aminophosphonic acids) is reviewed.
F Volckman, Janis, R. Hudson, Harry
core   +2 more sources

Cytotoxic Activity of Distinct Families of Phosphonic Acid Derivatives – A Chemocentric Approach to Assess Their Molecular Action

open access: yesChemMedChem, Volume 19, Issue 21, November 4, 2024.
Phosphonates represent unique chemical space among the biologically active compounds. Several compounds were measured on various human cancer cell lines and many of them showed remarkable cytotoxic activities. To assess their potential protein targets the structure of the hits were compared with known agents annotated with targets using fingerprint ...
György Dormán   +2 more
wiley   +1 more source

NH-Polyfluoroalkyl іminophosphonates in the synthesis of α-amino-α-polyfluoroalkyl-γ-oxobutylphosphonic acids

open access: yesЖурнал органічної та фармацевтичної хімії, 2019
Aim. To develop the preparative method for the synthesis of optically active α-amino-α-polyfluoroalkyl-γ-oxobutylphosphonic acids as new promising chiral building blocks. Results and discussion.
O. V. Stanko   +3 more
doaj   +1 more source

Catalytic Asymmetric Cycloadditions of Cyclic Sulfamidate Imines: Straightforward Access to Chiral N‐Heterocycles

open access: yesAdvanced Synthesis &Catalysis, Volume 366, Issue 19, Page 3926-3942, October 8, 2024.
Abstract Chiral N‐heterocyclic compounds are key structures in natural compounds and pharmaceuticals, and they serve as essential building blocks of functional materials. Catalytic asymmetric cycloaddition reactions represent one of the most efficient synthetic strategies for constructing optically active heterocycles.
Jong‐Un Park, Ju Hyun Kim
wiley   +1 more source

Antioxidant and anticancer activities of α-aminophosphonates containing thiadiazole moiety

open access: yesJournal of Saudi Chemical Society, 2018
In the current study, α-aminophosphonates containing thiadiazole moiety (1–4) was synthesized, characterized and their antioxidant and anticancer activities were carried out.
Mohamed M. Azaam   +4 more
doaj   +1 more source

New α-Aminophosphonates as Corrosion Inhibitors for Oil and Gas Pipelines Protection [PDF]

open access: yes, 2019
The problem of corrosion of metal equipment is one of the most actual problems in oil industry. One of the methods to solve this problem is the development of new low-toxic, accessible and effective corrosion inhibitors.
Kazimova, Kamila   +4 more
core   +1 more source

Green Metrics and Sustainability in Photocatalysis

open access: yesChemCatChem, Volume 16, Issue 14, July 22, 2024.
Lights and shadows in photocatalysis. This Review analyzes the sustainability of photoredox catalytic processes in the context of mass‐based metrics, highlighting significant sustainability issues in photocatalysts synthesis and in catalytic protocols, primarily driven by energy demanding preparations and by solvent intensive work‐up and purification ...
Arianna Quintavalla   +2 more
wiley   +1 more source

The kabachnik-fields and pudovik reactions on the basis of E,Z-citral and its imines and (R,S)-citronellal [PDF]

open access: yes, 2013
The Kabachnik-Fields reaction of E,Z-citral with diethyl phosphite in the presence of isobutylamine has been found to form α-aminophosphonates. The Pudovik reactions of diethyl phosphite with prenyl imines prepared on the basis of E,Z-citral with ...
Alfonsov V.   +3 more
core  

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