Results 111 to 120 of about 1,623,110 (217)

The endogenous opioid system in the medial prefrontal cortex mediates ketamine’s antidepressant-like actions

Translational Psychiatry
Recent studies have implicated the endogenous opioid system in the antidepressant actions of ketamine, but the underlying mechanisms remain unclear.
Cheng Jiang, Ralph J. DiLeone, Christopher Pittenger, Ronald S. Duman   +3 more
doaj   +1 more source

Molecular and Neuroendocrine Determinants of Seasonal Body Weight Regulation [PDF]

, 2005
This thesis deals with the characterisation of neuroendocrine pathways involved in seasonal body regulation revealed by the Siberian hamster (Phodopus sungorus).
Klingenspor, Martin (Dr.), Tups, Alexander   +1 more
core   +1 more source

Noradrenergic inhibition of definitive POMC neurons through direct and indirect mechanisms

Journal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Norepinephrine and the α2‐adrenoceptor agonist UK 14,304 robustly inhibit definitive arcuate POMC neurons. Direct inhibition is mediated by ADRA2A‐dependent activation of potassium conductances, while additional indirect mechanisms also contribute. In vivo, inducible POMC‐specific Adra2a deletion minimally affects energy balance and modestly impairs ...
Olivier Lavoie, Audrey Turmel, Axelle Khouma, Moein Minbashi Moeini, Chen Liu, Natalie J. Michael, Alexandre Caron   +6 more
wiley   +1 more source

Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists [PDF]

, 2016
It has now been demonstrated that the μ, δ(1), δ(2), and κ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R ...
Bailey A, Cowan A, Dhawan BN, Emmerson PJ, Fryer RM, Fryer RM, Fryer RM, Genade S, Grekova TI, Gu H, Haddad GG, Hansen DD, Hess L, Hiranuma T, Huh J, Imai N, Kettler D, Khan MG, Kin H, Kiritsy‐Roy JA, Kisin I, Korobov NV., Krazinski BE, Kulbertus H, Lasukova TV, Lasukova TV, Lasukova TV, Lasukova TV, Lasukova TV, Lishmanov AYu, Lishmanov IuB, Lishmanov IuB, Lishmanov YuB, Liu X, Marson L, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Metelitsa VI, Mikhailova SD, Monassier JP., Musha T, Panova EI., Pei JM, Platonov AA, Poonyachoti S, Pugsley MK, Pyle WG, Robson P., Saeed RW, Schultz JE, Shi E, Solenkova NV, Stefano GB, Sun HT, Ugdyzhekova DS, Varga EV, Wang GY, Wong GT, Zhang Y   +64 more
core   +2 more sources

Az endocannabinoid rendszer szerepe és szabályozása a humán faggyúmirigyben = Role and regulation of the endocannabinoid system in the human sebaceous gland [PDF]

, 2011
Nagymértékben fókuszált, alapkutatási projektünkben – melyet egy szakértő, multidiszciplináris kutatói team nemzetközi kollaboráció keretében valósított meg – szisztematikusan és mechanisztikusan térképeztük fel az endokannabinoid rendszer (ECS) szerepét
Borbíró, István, Bíró, Tamás, Czifra, Gabriella, Irinyi, Beatrix, Nagy, Miklós, Oláh, Attila, Szöllősi, Attila Gábor, Tóth, István Balázs   +7 more
core  

A novel delta opioid receptor specific peptide reduces craving in an animal model of cocaine seeking

Addiction Neuroscience
Substance use disorder, and particularly cocaine use disorder, is a complex disease that affects societal, economic, and psychological factors. Endogenous β-endorphin released after prolonged cocaine withdrawal has been reported to activate the accumbal ...
Pnina Shirel Itzhak-Israeli, Hevroni Yael, Erez Matsree, Hilla Pe'er-Nissan, Shira Ofer Lancman, Barnea R, Luboshits G, Menachem Motiei, Oshra Betzer, Iris Gispan, Rachela Popovtzer, Yaakov Anker, Firer MA, Yadid G   +13 more
doaj   +1 more source

β-Endorphin mediates radiation therapy fatigue. [PDF]

Sci Adv, 2022
Hermann AL, Fell GL, Kemény LV, Fung CY, Held KD, Biggs PJ, Rivera PD, Bilbo SD, Igras V, Willers H, Kung J, Gheorghiu L, Hideghéty K, Mao J, Woolf CJ, Fisher DE.   +15 more
europepmc   +1 more source

A Theory of Natural Addiction [PDF]

Economic theories of rational addiction aim to describe consumer behavior in the presence of habit-forming goods. We provide a biological foundation for this body of work by formally specifying conditions under which it is optimal to form a habit.
Smith, Trenton G., Tasnadi, Attila
core   +1 more source

Biochemical characterization of proopiomelanocortin variants in human and owls [PDF]

, 2015
In humans the proopiomelanocortin (POMC) gene is located on the short arm of the chromosome 2 at the 23.3 position and encodes a 39kDa peptide with 241 amino acids. This peptide is the precursor of the proopiomelanocortin prohormone and it is produced in
SAINT-ROCH, A.
core  

Biosignature of self-injury behaviors in adolescence: Role of β-endorphin in an acute inpatient unit. [PDF]

Front Psychiatry, 2022
Wang P, Li C, Del Sol-Calderón P, Mallol L, Hernández-Álvarez E, Donoso-Navarro E, Gil-Ligero M, Rosado-Garcia S, Sánchez-Lòpez AJ, Martín-Moratinos M, Bella-Fernández M, Blasco-Fontecilla H.   +11 more
europepmc   +1 more source