Results 171 to 180 of about 898,544 (258)

A Disproportionality Analysis of β‐lactam Antibiotic Related Blood and Lymphatic System Disorders Based on the FDA Adverse Event Reporting System Database

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims β‐lactam antibiotics stand as the most profoundly impactful classes of antibacterial agents worldwide. Their widespread application has raised safety concerns over adverse events (AEs), such as blood and lymphatic system disorders (BLSDs).
Jing Liu, Min Zhang, Zongwei Tang, Xiaoxiao Wang, Li Mu, Wanyi Chen, Haichi Song   +6 more
wiley   +1 more source

A Case Report of Left Pyelonephritis With Low‐Grade Contralateral Vesicoureteral Reflux After Robot‐Assisted Right Nephroureterectomy

IJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Introduction Pyelonephritis with contralateral vesicoureteral reflux (VUR) after robot‐assisted radical nephroureterectomy (RANU) in a solitary kidney has rarely been reported. Case Presentation A 73‐year‐old woman with preoperative lower urinary tract symptoms (LUTS; IPSS 15, OABSS 7) underwent right RANU for urothelial carcinoma of the renal
Shuhei Kusano, Shohei Tobu, Minika Yukimoto, Kyohei Matsushita, Akihiro Maeda, Yuka Kakinoki, Hiroaki Kakinoki, Maki Kawasaki, Mitsuru Noguchi   +8 more
wiley   +1 more source

Structure and function of metallo-β-lactamases. Meet-the-Experts session “Structure, Function and Genetics of Metallo-β-Lactamases”.

, 2011
Metallo-β-lactamases (Ambler’s class B, Bush-Jacoby’s classification group 3) are zinc-dependent enzymes able to hydrolyze a wide variety of β-lactam antibiotics, including oxyimino cephalosporins and carbapenems, while they are not inhibited by ...
DOCQUIER, JEAN DENIS
core   +1 more source

Standardized numbering and alignment of the KPC family of β-lactamases. [PDF]

Antimicrob Agents Chemother
Brunetti F, Marshall SH, Bethel CR, Hujer AM, Hujer KM, Haider S, Bush K, Bradford PA, Kreiswirth B, Spencer J, Ishii Y, Docquier J-D, Rossolini GM, Poirel L, Perilli M, Amicosante G, Galleni M, Vila AJ, Gutkind G, Palzkill T, Carattoli A, Tooke CL, Hinchliffe P, Schofield CJ, Iorga BI, Naas T, Chen Y, Arias C, Endimiani A, Papp-Wallace K, Shields RK, Tamma PD, Bonomo RA, Power P.   +33 more
europepmc   +1 more source

Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

iMetaOmics, Volume 3, Issue 3, September 2026.
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda, Patricio Arros, Nicolás Canales, Camilo Berríos‐Pastén, Gastón Azziz, Rosalba Lagos, Julieta Orlando, Francisco P. Chávez, Andrés E. Marcoleta   +8 more
wiley   +1 more source

Covalent inhibition of New Delhi metallo-β-lactamases NDM-1 and NDM-5 by 3-bromopyruvate. [PDF]

JAC Antimicrob Resist
Bradley JK, Tapia KC, Moyo SJ, Shore E, Nambala P, Hong WD, Schofield CJ, Roberts AP.   +7 more
europepmc   +1 more source

Dose Selection for Ceftibuten Combined with Avibactam Tomilopil, a Potential Oral Alternative to Carbapenems for Patients with Complicated Urinary Tract Infections

The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract There are currently no oral treatment options for infections caused by extended spectrum β‑lactamase‐producing Enterobacterales. Avibactam tomilopil, a novel oral prodrug of avibactam, is being developed in combination with the oral cephalosporin, ceftibuten, as a potential treatment for patients with complicated urinary tract infections ...
Siddhee A. Sahasrabudhe, Satoshi Shoji, Abhijeet S. Jakate, Bisrat K. Abraham, Sima S. Toussi, Benjamin J. Maligalig, Amanda S. Darekar, Sakambari Tripathy, Constantino Kantaridis, Josue K. Mfopou, Oxana Selivanova, Arthur Bergman, Negar Niki Alami, Ravi Shankar P. Singh   +13 more
wiley   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, Volume 57, Issue 9, Page 1554-1564, September 2026.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

Role of Ambler Position 104 in Defining Substrate Specificity in the KPC Family of β-Lactamases. [PDF]

ACS Infect Dis
Gao L, Marshall S, Bethel CR, Hujer AM, Taracila MA, Hujer KM, Haider S, Bonomo RA.   +7 more
europepmc   +1 more source

A Catalogue of Dispensation Lengths for Building Treatment Episodes—Application of the Waiting Time Distribution to All Commonly Prescribed Drugs in Denmark

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.
ABSTRACT Background In pharmacoepidemiologic research, correct assignment of the length of single dispensation is critical to build treatment episodes. The parametric reverse waiting time distribution (rWTD) is a particularly attractive data‐driven method to estimate dispensation lengths.
Mette Reilev, Lotte Rasmussen, Jonas Kanstrup Olsen, Martin Thomsen Ernst, Saad Hanif Abbasi, Rikke Wesselhoeft, Mette Bliddal, Jesper Hallas, Henrik Støvring   +8 more
wiley   +1 more source