Results 161 to 170 of about 3,518,946 (289)

Almost α-γ-Irresolute Functions

Journal of New Results in Science, 2014
functions called almost γ-irresolute functions and almost α-γirresolute functions in topological spaces. We obtain several characterizations of these classes and study their properties and investigate the relationships with the known non-continuous ...
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Structural basis of active state coupling of metabotropic glutamate receptor 8 to beta-arrestins. [PDF]

Nat Commun
Marx DC, Huynh K, Gonzalez-Hernandez AJ, Strauss A, Rico C, Gallo PN, Sharghi Moshtaghin S, Arefin A, Broichhagen J, Eliezer D, Khelashvili G, Levitz J.   +11 more
europepmc   +1 more source

Μονάς and ψυχή in the Phaedo

PLATO JOURNAL, 2018
The paper analyzes the final proof with Greek mathematics and the possibility of intermediates in the Phaedo. The final proof in Plato’s Phaedo depends on a claim at 105c6, that μονάς, unit’, generates περιττός odd’in number. So, ψυχή soul’generates ζωή life’in a body, at 105c10-11.
openaire   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

AS160 Overexpression Protects Against β-Cell Failure in Hyperglycemic Mice by Interacting With HSPA8 to Regulate Mitophagy. [PDF]

Acta Physiol (Oxf)
Chen W, Lu Y, Liu X, Huang B, Liu D, He B, Zhao Z, Wang Q, Li J, Xiong W.   +9 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Postnatal refinement of Ca_V channel isoform composition, electrical activity, and insulin release in mouse pancreatic β-cells. [PDF]

Channels (Austin)
Theiner T, Jacobo-Piqueras N, Tota D, Tuluc P.   +3 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Molecular-Level Characterization of Native Lignin Oligomers From Flow-Through Solvolysis of Biomass by High-Performance Liquid Chromatography-Tandem Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
Zhou Z, Zhu L, Xiao X, Cui C, Qi F.
europepmc   +1 more source