Changes in the Level of Antiphospholipid Antibodies (Anticardiolipin and Anti-β2-Glycoprotein-I) and Thromboembolic Indices in COVID-19 Patients during 3 Weeks [PDF]
International Journal of Preventive Medicine, 2023 Introduction: COVID-19 is a respiratory disease caused by infection with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). Thrombotic complications appear to be of particular importance in patients with COVID-19.
Somayeh Haghighipour +5 more
doaj +2 more sources
β2-glycoprotein I promotes the clearance of circulating mitochondria. [PDF]
PLoS ONEβ2-glycoprotein I (β2-Gp1) is a cardiolipin-binding plasma glycoprotein. It is evolutionarily conserved from invertebrates, and cardiolipin-bound β2-Gp1 is a major target of antiphospholipid antibodies seen in autoimmune disorders.
Swapan Kumar Dasgupta +5 more
doaj +4 more sources
Epitope of antiphospholipid antibodies retrieved from peptide microarray based on R39‐R43 of β2‐glycoprotein I [PDF]
Research and Practice in Thrombosis and Haemostasis, 2022 Background Antiphospholipid antibody (aPL) syndrome (APS) is an autoimmune disease characterized by the presence of antiphospholipid antibodies and thromboembolic or pregnancy complications.
Marc Moghbel +8 more
doaj +2 more sources
Anticardiolipin and/or anti-β2-glycoprotein-I antibodies are associated with adverse IVF outcomes [PDF]
Frontiers in Immunology, 2022 ObjectiveThe purpose of the study is to evaluate the effects of anticardiolipin (aCL) and/or anti-β2-glycoprotein-I (aβ2GPI) antibodies, namely antiphospholipid antibodies (aPL), on in vitro fertilization (IVF) outcomes.Materials and methodsThe study ...
Li Wu +6 more
doaj +2 more sources
β2-Glycoprotein I-Reactive T Cells in Autoimmune Disease [PDF]
Frontiers in Immunology, 2018 Anti-phospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are autoimmune diseases characterized by autoantibody production and autoantibody-related pathology.
Joyce Rauch +4 more
doaj +2 more sources
Antigenic assessment for the β2-glycoprotein I/Platelet factor 4 complex in thrombotic patients with antiphospholipid syndrome [PDF]
Frontiers in ImmunologyObjectiveAntiphospholipid syndrome (APS) is an autoimmune condition characterized by recurrent thrombosis, pregnancy-related complications and circulating antiphospholipid antibodies, including anti-β2-glycoprotein I (β2-GPI).
Francesca Villani +14 more
doaj +2 more sources
Optimization of Unnicked β2-Glycoprotein I and High Avidity Anti-β2-Glycoprotein I Antibodies Isolation [PDF]
Journal of Immunology Research, 2014 Patient biological material for isolation of β2-glycoprotein I (β2GPI) and high avidity IgG anti-β2-glycoprotein I antibodies (HAv anti-β2GPI) dictates its full utilization.
Andrej Artenjak +6 more
doaj +2 more sources
The purification of reduced β2-glycoprotein I showed its native activity in vitro [PDF]
Lipids in Health and Disease, 2017 Background New evidence has shown that reduced β2-glycoprotein I (β2GPI) has anti-oxidative stress and anti-inflammatory activity. However, the details are still poorly understood.
Saijun Zhou +7 more
doaj +2 more sources
IgA anti-β2-glycoprotein I as an independent risk factor in acute venous thromboembolism [PDF]
Frontiers in ImmunologyBackgroundVenous thromboembolism (VTE) is the third most common cause of cardiovascular death. Primary Antiphospholipid Syndrome (P-APS) is a chronic systemic autoimmune disorder characterized by thrombotic events and/or obstetric complications in ...
Raquel Diaz-Simon +34 more
doaj +2 more sources
Tolerogenic β2-glycoprotein I DNA vaccine and FK506 as an adjuvant attenuates experimental obstetric antiphospholipid syndrome. [PDF]
PLoS ONE, 2018 DNA vaccines have recently emerged as a therapeutic agent for treating autoimmune diseases, such as multiple sclerosis. Antiphospholipid antibody syndrome (APS) is an autoimmune disease characterized by β2-glycoprotein I (β2-GPI)-targeting ...
Ya-Hsuan Chao +4 more
doaj +2 more sources