DreamFold: A World Model to efficiently generate protein folding pathways in the latent space
Protein Science, Volume 35, Issue 11, November 2026.Abstract While there is an abundance of static data for the structure of biological macromolecules, the data regarding their folding mechanisms and dynamics is scarce, posing a challenge to the training of AI models. The World Model approach, which has been very successful in robotics, can come in handy in this regard. From limited data, it can build a
Alan Ianeselli +3 more
wiley +1 more source
, 2018 Hombre de 45 años de edad que acudió a consulta por lateropulsión a la izquierda y mareos. La tomografía de cráneo mostró infarto cerebelar bilateral.
Santiago, Noé +5 more
core
Bacterial sialidases subvert the complement system through desialylation
Protein Science, Volume 35, Issue 11, November 2026.Abstract Bacterial sialidases (neuraminidases) are widely studied virulence factors, yet their impact on the complement system, a central component of innate immunity, remains poorly understood. Here, we investigate the effects of six sialidases from five human pathogens, including Bacteroides fragilis, Clostridium perfringens, Tannerella forsythia ...
Kurni Kurniyati +6 more
wiley +1 more source
Interference in point-of-care international normalized ratio monitoring in patients with lupus anticoagulant is correlated with anti-β2-glycoprotein I antibody titers. [PDF]
Res Pract Thromb Haemost, 2023 Noordermeer T +7 more
europepmc +1 more source
Vitamin D: Physiology, Pharmacology and Clinical Evidence for Supplementation—A Narrative Review
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.ABSTRACT Vitamin D is a nutrient and prohormone obtained from diet and supplements and synthesized in the skin. It is essential for calcium and phosphate homeostasis and skeletal health and influences multiple extra‐skeletal processes, yet deficiency remains common worldwide.
Jyrki K. Virtanen
wiley +1 more source
Evidence of Thrombogenesis Recurrence Induced by IgA Antiphospholipid Antibody β2 Glycoprotein I-Dependent in Early Adulthood. [PDF]
Cureus, 2022 Yacoub MS +3 more
europepmc +1 more source
Subclinical Cerebral Lesions in Migraine: A Proof‐of‐Concept Study on Platelet Aggregation
European Journal of Neurology, Volume 33, Issue 11, November 2026.We assessed platelet aggregation in patients with migraine (n = 34) with or without cerebral white‐matter lesions (WMLs) versus matched controls (n = 34), with WMLs volume quantified by MRI (mm3). Aggregation to ADP, collagen, epinephrine, and arachidonic acid was measured; epinephrine‐induced aggregation at 1.25–2.5 μM was overall lower in migraine ...
Ilaria Maestrini +10 more
wiley +1 more source
Journal of Food Process Engineering, Volume 49, Issue 11, November 2026.Graphical representation of the response surface methodology (RSM) framework applied to optimize roasting temperature (150°C–220°C) and time (10–20 min) in pulses. Optimized processing and subsequent milling produce roasted bean flour with significantly reduced lectin content and improved phytochemical profiles and antioxidant activity.
Olumide O. Fashakin +2 more
wiley +1 more source
β2 glycoprotein I participates in phagocytosis of apoptotic neurons and in vascular injury in experimental brain stroke. [PDF]
J Cereb Blood Flow Metab, 2021 Grossi C +9 more
europepmc +1 more source
Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules
Plant Biotechnology Journal, Volume 24, Issue 11, Page 5616-5630, November 2026.ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan +8 more
wiley +1 more source