Results 71 to 80 of about 2,136 (147)

Radiolabelled peptides for oncological diagnosis [PDF]

open access: yes, 2012
Radiolabelled receptor-binding peptides targeting receptors (over)expressed on tumour cells are widely under investigation for tumour diagnosis and therapy.
Peter Laverman   +3 more
core   +1 more source

Comblike ionic complexes of hyaluronic acid and alkanoylcholine surfactants as a platform for drug delivery systems [PDF]

open access: yes, 2018
Nontoxic alkanoylcholine soaps (nACh) were synthesized from choline and fatty acids with numbers of carbons n equal to 12, 14, 16, and 18, the latter including both saturated and 9-cis unsaturated alkanoyl chains.
Gamarra Montes, Ana   +4 more
core   +1 more source

Development of a DNA Vaccine for Melanoma Metastasis by Inhalation Based on an Analysis of Transgene Expression Characteristics of Naked pDNA and a Ternary Complex in Mouse Lung Tissues

open access: yesPharmaceutics, 2020
The present study investigated a pulmonary delivery system of plasmid DNA (pDNA) and its application to melanoma DNA vaccines. pCMV-Luc, pEGFP-C1, and pZsGreen were used as a model pDNA to evaluate transfection efficacy after inhalation in mice.
Yukinobu Kodama   +14 more
doaj   +1 more source

From Residues to Added-Value Bacterial Biopolymers as Nanomaterials for Biomedical Applications

open access: yesNanomaterials, 2021
Bacterial biopolymers are naturally occurring materials comprising a wide range of molecules with diverse chemical structures that can be produced from renewable sources following the principles of the circular economy.
Francisco G. Blanco   +7 more
doaj   +1 more source

Study of fluvial water treatability using γ-polyglutamic acid based biopolymer coagulant

open access: yesAnais da Academia Brasileira de Ciências
: Successful treatment of surface water for public use requires the evaluation of raw water and coagulant efficacy. The purpose of water treatment is to remove impurities, allowing its quality to be classified to meet the needs of the population.
VALQUÍRIA CAMPOS   +3 more
doaj   +1 more source

Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells [PDF]

open access: yes, 2017
Giant amphiphiles encompassing a hydrophilic β-cyclodextrin (βCD) component and a hydrophobic calix[4]arene (CA4) module undergo self-assembly in aqueous media to afford core-shell nanospheres or nanocapsules, depending on the nanoprecipitation protocol,
Casnati, Alessandro   +8 more
core   +2 more sources

Isolation and characterization of an exopolymer produced by bacillus licheniformis: in vitro antiviral activity against enveloped viruses [PDF]

open access: yes, 2020
The exopolymer (EPSp) produced by the strain B. licheniformis IDN-EC was isolated and characterized using different techniques (MALDI-TOF, NMR, ATR-FTIR, TGA, DSC, SEM).
Abrusci, Concepción   +6 more
core   +2 more sources

Suitable Promoter for DNA Vaccination Using a pDNA Ternary Complex

open access: yesPharmaceutics
In this study, we evaluated the effect of several promoters on the transfection activity and immune-induction efficiency of a plasmid DNA (pDNA)/polyethylenimine/γ-polyglutamic acid complex (pDNA ternary complex). Model pDNAs encoding firefly luciferase (
Tomoaki Kurosaki   +3 more
doaj   +1 more source

Effectiveness evaluation of hyaluronic acid-based commercial eye drops to treat ophthalmic dry eye disease

open access: yesCarbohydrate Polymer Technologies and Applications
Nowadays, hyaluronic acid (HA) eye drops are widely used to combat ophthalmic dry eye disease (DED). Till the date, almost all commercialized HA eye drops are single-ingredient despite not displaying significantly different clinical effects (Artelac ...
Jon Andrade del Olmo   +7 more
doaj   +1 more source

Microbial γ-polyglutamic acid (γ-PGA) incorporation into muffins: Impact on physico-chemical, functional, and textural properties

open access: yesFrontiers in Food Science and Technology
This study investigated the effects of gamma‐(γ)‐polyglutamic acid (γ‐PGA) on the physical, structural, and sensory properties of muffins. γ‐PGA polymer, extracted from Bacillus valezensis M‐E6, was incorporated into muffin batter at concentrations ...
Verma Manika   +5 more
doaj   +1 more source

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