Results 101 to 110 of about 95,923 (169)

Simultaneous Representation Learning of Multi-Omics and Clinical Outcome Data via a Supervised Knowledge-Guided Bayesian Factor Model. [PDF]

Stat Med
Zhang Q, Chang C, Jin C, Shen L, Long Q.
europepmc   +1 more source

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review). [PDF]

Int J Mol Med
Dai W, Wu J, Ma X, Wu M, Li K, Gao H, Wang W, Xiao W.   +7 more
europepmc   +1 more source

RHINO: An Integrative Multi‐Omics Framework Linking Circadian Physiology to Precision Medicine

Advanced Science, EarlyView.
RHINO (RHythmic Interacting Network for multi‐Omics) is an integrative framework that maps circadian regulation across diverse genetic and disease contexts and prioritizes druggable circadian targets. Released as an AI‐powered interactive web portal, RHINO unifies genetic, regulatory, disease, and drug–target information, enabling context‐specific ...
Ying Chen, Chengxuan Chen, Dishu Zhou, Panpan Liu, Roberto E. López‐Valiente, Yuan Liu, Cam Mong La, Isabella Beraldo Xavier, Sean M. Hartig, Pradip Saha, Zheng Sun, Leng Han, Dongyin Guan   +12 more
wiley   +1 more source

Estimation of ED50 and ED95 of oliceridine required to suppress bronchoscopic responses during remimazolam sedation: study protocol for an up-and-down sequential allocation trial. [PDF]

BMJ Open
Li A, Zhou Y, Zhou X, Jiang K, Hu B.
europepmc   +1 more source

Lightweight, Elastic Ceramic Fabrics for Broadband Electromagnetic Absorption and High Temperature Thermal Insulation

Advanced Science, EarlyView.
This study reports lightweight, elastic ceramic fabrics with broadband electromagnetic absorption (EAB = 9.8 GHz) and high‐temperature thermal insulation, enabled by precise microstructural control during ultrafast high‐temperature sintering (UHS), which induces the precipitation of defect‐rich t‐ZrO2 nanograins and turbostratic C nanoclusters.
Jiahao Yang, Qi Ding, Juanjuan Xu, Fei Yan, Rui Wang, Yuena Zhang, Chao Zhao, Zhi Cheng, Yuchi Fan, Wan Jiang   +9 more
wiley   +1 more source

Measurement effects on critical scaling in neural systems. [PDF]

Front Comput Neurosci
Li MS, Liu B, van Antwerp KW, Abdelaleem E, Sederberg AJ.   +4 more
europepmc   +1 more source

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

Nanoperlite Particles Enhance Fibrogenesis in Thyroid Orbital Fibroblasts: A Potential Activated Cell Source for Ocular Tissue Engineering. [PDF]

Biomed Res Int
Sanie-Jahromi F, Sahraeian R, Khademi B.
europepmc   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source