Results 221 to 230 of about 31,247 (253)

A µ-opioid receptor modulator that works cooperatively with naloxone. [PDF]

Nature
O'Brien ES, Rangari VA, El Daibani A, Eans SO, Hammond HR, White E, Wang H, Shiimura Y, Krishna Kumar K, Jiang Q, Appourchaux K, Huang W, Zhang C, Kennedy BJ, Mathiesen JM, Che T, McLaughlin JP, Majumdar S, Kobilka BK.   +18 more
europepmc   +1 more source

Developing predictive models for µ opioid receptor binding using machine learning and deep learning techniques. [PDF]

Exp Biol Med (Maywood)
Liu J, Li J, Li Z, Dong F, Guo W, Ge W, Patterson TA, Hong H.   +7 more
europepmc   +1 more source

Association of <i>ABCB1</i>, μ-opioid Receptor, and Cytochrome <i>P450</i> Genes with Methadone Dose in Iranian Male Addicts Under Methadone Therapy. [PDF]

Basic Clin Neurosci
Golnezhad A, Torkaman-Boutorabi A, Mohammad Razaghi E, Zarrindast MR, Mahdavi MR, Vousooghi N.   +5 more
europepmc   +1 more source

Effect of A118G (rs1799971) single-nucleotide polymorphism of the μ-opioid receptor OPRM1 gene on intraoperative remifentanil requirements in Japanese women undergoing laparoscopic gynecological surgery. [PDF]

Neuropsychopharmacol Rep
Zou R, Nishizawa D, Inoue R, Hasegawa J, Ebata Y, Nakayama K, Hara A, Sumikura H, Kitade M, Hayashida M, Ikeda K, Kawagoe I.   +11 more
europepmc   +1 more source

Carfentanil stabilizes µ opioid receptor conformations that are ultra-efficient in inhibiting cAMP, resistant to naloxone or nalmefene but sensitive to naltrexone. [PDF]

Arch Toxicol
Endt F, Guo T, Steinritz D, Amend N, Gudermann T, Breit A.   +5 more
europepmc   +1 more source

In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling. [PDF]

ACS Chem Neurosci
Tsai MM, Chen L, Baumann MH, Canals M, Javitch JA, Lane JR, Shi L.   +6 more
europepmc   +1 more source

Profiling the proximal proteome of the activated μ-opioid receptor. [PDF]

Nat Chem Biol
Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Hernandez AJ, Xu J, Li Q, Novy B, Naing ZZC, Shoichet BK, Coyote-Maestas W, Levitz J, Krogan NJ, Von Zastrow M, Hüttenhain R.   +16 more
europepmc   +1 more source

Stereoselective recognition of morphine enantiomers by μ-opioid receptor. [PDF]

Natl Sci Rev
Wang Y, Ngo VA, Wang X.
europepmc   +1 more source

Potency, dissociation kinetics and reversibility of fentanyls and nitazenes by naloxone at the μ opioid receptor

Alhosan N, Cavallo D, Santiago M, Kelly E, Henderson G.   +4 more
europepmc   +1 more source

Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. [PDF]

Nature
Zhao J, Elgeti M, O'Brien ES, Sár CP, Ei Daibani A, Heng J, Sun X, White E, Che T, Hubbell WL, Kobilka BK, Chen C.   +11 more
europepmc   +1 more source