Results 41 to 50 of about 273,008 (258)

4-{(E)-[(2-Hydroxynaphthalen-1-yl)methylidene]amino}-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one: a new polymorph (β-phase)

open access: yesIUCrData, 2017
The title molecule, C22H19N3O2, is a new polymorphic modification, viz. the β-phase; the α-phase has been previously published [Liang & Wang (2010). Acta Cryst. E66, o1968–o1969].
Shaaban K. Mohamed   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Anisotropy of π–π Stacking as Basis for Superlubricity [PDF]

open access: yes
When two surfaces move against each other, often high adhesive strength with low friction is desired. Then, the interfacial interaction requires a strong directional anisotropy, as provided by π–π stacking.
Johanna L. Trefs (14247762)   +3 more
core   +1 more source

Anisotropic Dynamic Disorder of π‐Stacking and Static Disorder in Organic Electron Transporting Materials with Isomorphic Crystal Structures

open access: yesSmall Structures
In organic semiconductors, charge transport is strongly correlated with intermolecular π–π interactions and the dynamic disorder caused by solid‐state phonon vibrations.
Chae‐Won Lee   +14 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Residues involved in π-π stacking interactions in AnBLUF65 dark-(orange) and light-adapted (blue) state. [PDF]

open access: yes, 2022
Residues involved in π-π stacking interactions in AnBLUF65 dark-(orange) and light-adapted (blue) state.
Claudio D. Borsarelli (1962889)   +7 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

π–π Stacking Mediated Chirality in Functional Supramolecular Filaments [PDF]

open access: yes, 2016
While a great diversity of peptide-based supramolecular filaments have been reported, the impact of an auxiliary segment on the chiral assembly of peptides remains poorly understood.
Pengcheng Zhang (565544)   +3 more
core   +1 more source

Unveiling how intramolecular stacking modes of covalently linked dimers dictate photoswitching properties

open access: yesNature Communications, 2019
Covalently bridged π-stacked dimers are excellent molecular platforms for understanding the relationship between stacking orientation and properties. Here, the authors synthesize a pair of π-stacked dimers that are aligned either cofacially or crosswise,
Ru-Qiang Lu   +14 more
doaj   +1 more source

6-[6-(Pyridin-2-yl)-1,2,4,5-tetrazin-3-yl]pyridin-3-amine monohydrate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
The packing of the title compound, C12H9N7·H2O, is dominated by hydrogen bonding and π-stacking. Layers parallel to [010] are established by hydrogen bonds involving all amine donor functions and one of the water donor functions, while the remaining ...
Johannes Broichhagen   +3 more
doaj   +1 more source

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