Results 81 to 90 of about 9,489,591 (252)

Collective Phase Sensitivity

, 2008
The collective phase response to a macroscopic external perturbation of a population of interacting nonlinear elements exhibiting collective oscillations is formulated for the case of globally-coupled oscillators.
A. T. Winfree, Hiroshi Kori, Hiroya Nakao, Kensuke Arai, S. C. Manrubia, Y. Kuramoto, Yoji Kawamura, Yoshiki Kuramoto   +7 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

CKM Phase Measurements

, 2004
Recent experimental results on CP violation in the B sector from BABAR and BELLE, experiments at asymmetric e+e- B-Factories, are summarized in these proceedings.
Ganzhur, Sergey
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Spontaneous CP Violating Phase as The CKM Matrix Phase

, 2007
We propose that the CP violating phase in the CKM mixing matrix is identical to the CP phases responsible for the spontaneous CP violation in the Higgs potential. A specific multi-Higgs model with Peccei-Quinn (PQ) symmetry is constructed to realize this
A.R. Zhitnitsky, B. Pontecovo, B.H.J. McKellar, C.Q. Geng, D. Chang, D. Chang, D. Chang, E. Braaten, E. Braaten, G. Beall, G.C. Branco, G.C. Branco, G.C. Branco, H. Fusaoka, I.I.Y. Bigi, J.E. Kim, J.F. Gunion, Jing Jiang, K. Babu, Lu-Hsing Tsai, M. Dine, M. Kobayashi, M. Okamoto, M. Shifman, N. Cabibbo, N.G. Deshpande, N.G. Deshpande, P. Ball, R. Akhoury, R.D. Peccei, R.D. Peccei, S. Weinberg, S. Weinberg, S. Weinberg, S.M. Barr, S.M. Barr, Shao-Long Chen, T.D. Lee, T.D. Lee, W.-M. Yao, X.G. He, X.G. He, X.G. He, X.G. He, X.G. He, X.G. He, Xiao-Gang He, Z. Maki   +47 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Effect of Cr and Mo on σ- Phase Precipitation Behavior and Pitting Corrosion Resistance Properties of Ultra-Low-Carbon Dual Phase Stainless Steel

Teshugang, 2015
The σ-phase precipitation rule in four kinds of typical ultra-low-carbon dual phase stainless steel 00Cr21Ni2Mn5N, 00Cr22Ni5Mo3N, 00Cr25Ni7Mo3N and 00Cr27Ni7Mo5N solid-solution-treaded at 1 050 ~ 1 120 °C and aged at 500 ~ 1 100 °C and the effect of σ ...
李惠, 宋志刚, 丰涵, 郑文杰, 张颖   +4 more
doaj  

Scaling of Berry's Phase Close to the Dicke Quantum Phase Transition

, 2006
We discuss the thermodynamic and finite size scaling properties of the geometric phase in the adiabatic Dicke model, describing the super-radiant phase transition for an $N$ qubit register coupled to a slow oscillator mode.
A Carollo, Berry M. V., Bohm A., F Plastina, G Liberti, Hamma A., Liberti G., Longuet-Higgins H. C., Orszag M., Sachdev S., Shapere A.   +10 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source