Results 21 to 30 of about 681,265 (180)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Determination of pion and kaon fragmentation functions including spin asymmetries data in a global analysis

, 2013
We present new functional form of pion and kaon fragmentation functions up to next-to-leading order obtained through a global fit to single-inclusive electron-positron annihilation data and also employ, the semi-inclusive deep inelastic scattering ...
Arbabifar, F., Khorramian, A. N., Nejad, S. M. Moosavi, Soleymaninia, M.   +3 more
core   +1 more source

On the Role of Visuals in Multimodal Answers to Medical Questions [PDF]

, 2007
This paper describes two experiments carried out in order to investigate the role of visuals in multimodal answer presentations for a medical question answering system.
Bosma, Wauter, Hooijdonk, Charlotte van, Krahmer, Emiel, Maes, Alfons, Theune, Mariët, Vos, Jurry de   +5 more
core   +4 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Efficient analysis in planet transit surveys [PDF]

, 2005
With the growing number of projects dedicated to the search for extrasolar planets via transits, there is a need to develop fast, automatic, robust methods with a statistical background in order to efficiently do the analysis.
A. Schwarzenberg-Czerny, Beaulieu, Beaulieu, Beaulieu, Bouchy, Brandt, Carpano, Charbonneau, Claret, Cumming, Davies, Defay, Deming, Doyle, Eadie, Fisher, Fisz, Gregory, Horne, J.-Ph. Beaulieu, Jenkins, Konacki, Kovacs, Lomb, Press, Schwarzenberg-Czerny, Schwarzenberg-Czerny, Schwarzenberg-Czerny, Schwarzenberg-Czerny, Stellingwerf, Struve, Tingley, Tingley, Udalski, Udalski, van Leeuwen, Weldrake, Whittaker   +37 more
core   +4 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Application of Bayesian graphs to SN Ia data analysis and compression [PDF]

, 2016
Bayesian graphical models are an efficient tool for modelling complex data and derive self-consistent expressions of the posterior distribution of model parameters.
Bruce A. Bassett, Cong Ma, Dovì, Huterer, Mosher, Patil, Pier-Stefano Corasaniti, Rao, Rubin, Tripp, White, Wigner   +11 more
core   +4 more sources

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Parton Distributions

, 2005
I present an overview of some current topics in the measurement of Parton Distribution Functions.Comment: 13 pages, 9 figures. Plenary talk presented at the XIII International Workshop on Deep Inelastic Scattering (DIS 2005), Madison WI USA, April 27-
Pumplin, Jon
core   +1 more source