Results 221 to 230 of about 974,832 (231)

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

The effect of reminder mobile application use on medication adherence after total thyroidectomy: a randomized controlled trial. [PDF]

Support Care Cancer
Kaya P, Erden S.
europepmc   +1 more source

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

Advanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao, Xiaofan Jiang, Md Moniruzzaman, Alexandra Mueller, Taskeen Iqbal Janjua, Nisha Tyagi, Zhi Qu, Kuan Yau Wong, Yuran Feng, Aayushi Ghodasara, Ekaterina Strounina, Benjamin P. Ross, Tushar Kumeria, Sumaira Z. Hasnain, Amirali Popat   +14 more
wiley   +1 more source

Correction: The neutrophil to high-density lipoprotein cholesterol ratio is associated with disease severity in hypertriglyceridemic acute pancreatitis. [PDF]

BMC Gastroenterol
Hu X, Xu J, Yang J, Liu M.
europepmc   +1 more source

Wavy‐Interlocked Stretchable Triboelectric Nanogenerators Enhanced by Liquid Metal Microflowers for Self‐Powered Wearable Motion Monitoring

Advanced Science, EarlyView.
Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu, Huimin Li, Hanmin Zeng, Yahui Meng, Yimeng He, Xinke Hu, Senfeng Zhao, Jianxun Zhang, Peiqiong Zhou, Kechao Zhou, Dou Zhang, Chris Bowen, Yan Zhang   +12 more
wiley   +1 more source

Clinical and Radiographic Evaluation of Photodynamic Therapy in Root Canal Treatment of Primary Molars: A 15-month Randomized Clinical Trial. [PDF]

Int J Clin Pediatr Dent
Farrag MEA, El Agamy RAA, El Kalla IH, Abdellatif AM.   +3 more
europepmc   +1 more source

Effectiveness of <i>Streptococcus salivarius</i> probiotics on alleviating radiation-induced oral mucositis via inflammatory and microecological modulation: a prospective pragmatic interventional study in nasopharyngeal carcinoma. [PDF]

Front Immunol
Huang XT, Feng H, Tan Y, Wang Q, Wei JM, Huang ZD, Wang XT, Lu HJ.   +7 more
europepmc   +1 more source

Psychological resilience and professional quality of life among surgical nurses: a cross-sectional study. [PDF]

BMC Psychol
Mutlu S, Yılmaz E.
europepmc   +1 more source

Impact of Transitioning Elective Orthopedic Surgeries to the Ambulatory Setting on Acute-Care Hospital Operations and Quality. [PDF]

Cureus
Turcotte J, Johnson AH, Nallani MC, Ley CD, King PJ, Perkins SB.   +5 more
europepmc   +1 more source

Efficacy of Percutaneous Vertebroplasty Assisted by a Curved Cement Delivery Guide for Osteoporotic Vertebral Compression Fractures in the Elderly. [PDF]

Clin Interv Aging
Li M, Liang M, Xiang Y, Yan A, Yang W, Xu R, Zhang T.   +6 more
europepmc   +1 more source