Analysis of associations between pharmacodynamic genetic factors and antipsychotics’ effectiveness and safety in adolescents with acute psychotic episodes taking antipsychotics during a 28-day follow-up [PDF]
Introduction. Antipsychotics are the main drugs for treatment of schizophrenia spectrum disorders. Pharmacodynamic genetic factors are being actively studied to improve the accuracy of antipsychotic selection based on pharmacogenetic testing.
D. V. Ivaschenko +11 more
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Risk management of metabolic disorders in the use of antipsychotics [PDF]
Cardio-metabolic risk factors and diabetes mellitus type 2 are highly prevalent in patients with schizophrenia. Decrease of metabolic risks associated with use of atypical antipsychotics is connected with the development of specialised programs. They can
G. E. Mazo, A. O. Kibitov
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Is the «equivalent chlorpromazine» dose in psychopharmacotherapy consistent with Good Clinical Practice? [PDF]
Principles of adequate pharmacotherapy in psychiatry imply that shifting from one antipsychotic to another requires recalculation of the effective dose using the «chlorpromazine equivalent».
M. Yu. Popov, P. V. Kozlovskaya
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Pharmacogenetics of antipsychotic-induced metabolic disturbances: state-of-the-art [PDF]
Antipsychotics are the main pharmaceutical agents in treatment of schizophrenia and other mental disorders. According to literature data up to 60% of patients with schizophrenia have antipsychotic-induced metabolic disturbances.
R. F. Nasyrova +9 more
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Budget impact of modern drugs for the treatment of schizophrenia: regional aspects [PDF]
The article presents the results of comparative pharmacoeconomic analysis of treatment of schizophrenia with antipsychotics of the first and second generation in Khabarovsk territory.
K. V. Krot +2 more
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Hyperprolactinemia during application of second-generation antipsychotics: the principles of prevention, diagnosis and correction [PDF]
The article presents compelling evidence of the need to draw attention of physicians to the problem of neyroleptical hyperprolactinemia. The article provides information about different prolactogen activity of antipsychotics with the release of the ...
L. N. Gorobets, G. E. Mazo
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Фармакоэкономический анализ эффективности затрат современных атипичных антипсихотиков у больных шизофренией [PDF]
Актуальность. Около 15% от всех больных с шизофрений трудоспособного возраста, состоящих под диспансерным наблюдением, попадают в группу пациентов с неустойчивой трудовой адаптацией.
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Мультифакторный клиникоэкономический анализ эффективности применения современных атипичных антипсихотиков у больных с шизофренией [PDF]
Актуальность. Учитывая высокую социальную значимость шизофрении, особенно при ограниченных возможностях реадаптации и ресоциализации пациентов с шизофренией в текущих условиях функционирования психиатрической службы, а также значительную финансовую ...
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Patient social function and quality of life in schizophrenia: focus on paliperidone palmitate [PDF]
The long-term outcomes of treatment with new selective antipsychotic for patients with schizophrenia have been discussed. Using the example of patients treated with “Xeplion” for secondary prevention of worsening symptoms of the disorder and changing in ...
E. V. Grigorieva
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Цель: Изучение роли носительства полиморфного варианта гена LEP (rs3828942) в развитии антипсихотикиндуцированных нарушении углеводного обмена у пациентов с шизофрениеи, постоянно проживающих в европеискои части Россиискои Федерации. Материалы и методы:
Добродеева, В.С. +4 more
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