Results 1 to 10 of about 15 (15)

INTERCHANGEABILITY OF MYOCARDIAL CYTOPROTECTORS IN PATIENTS WITH ISCHEMIC HEART DISEASE. DIFFICULT QUESTIONS –SIMPLE SOLUTIONS

open access: yesРациональная фармакотерапия в кардиологии, 2015
Indications for myocardial cytoprotector, trimetazidine, in patients with ischemic heart disease are analyzed and justified according to evidence based medicine.
Zh. M. Sizova
doaj   +1 more source

ASSESSMENT OF THERAPEUTICAL EQUIVALENCY OF ORIGINAL AND GENERIC INDAPAMIDE IN HYPERTENSIVE PATIENTS BY RANDOMIZED CROSS-OVER STUDY

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To develop a protocol for comparison of efficacy and safety of original drugs with generic ones and to apply this protocol for comparison of generic indapamide (Indap) with original indapamide in two presentations: short acting (Arifon) and long ...
N. P. Kutishenko   +3 more
doaj   +1 more source

THERAPEUTIC EQUIVALENCE OF ORIGINAL CLOPIDOGREL (PLAVIX) AND ITS GENERIC (EGITROMB). RESULTS OF COMPARATIVE RANDOMIZED CROSS-OVER BLIND STUDY

open access: yesРациональная фармакотерапия в кардиологии, 2016
Aim. To study therapeutic equivalence (efficacy, safety and tolerability) of original clopidogrel (Plavix) and its generic (Egitromb) in patients of high cardiovascular risk. Material and methods.
V. V. Yakusevich   +4 more
doaj   +1 more source

STATIN GENERICS: EFFICACY AND SAFETY RATIO

open access: yesРациональная фармакотерапия в кардиологии, 2016
Statin usage for primary and secondary prevention of cardiovascular diseases is focused. Rational choice between original and generic drugs is discussed taking into account efficacy and safety ratio.
V. P. Voronina   +4 more
doaj   +1 more source

THE KARDIOKANON STUDY: A WAY TO SETTLE THE SUBJECT OF CLINICAL EQUIVALENCE OF GENERIC AND ORIGINAL DRUGS

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To compare two therapies based on the use of original or generic drugs in patients with stable ischemic heart disease (IHD). Material and methods.
S. Yu. Martsevich   +6 more
doaj   +1 more source

A COMPARATIVE STUDY OF EFFICACY AND TOLERABILITY OF GENERIC AND ORIGINAL LOW-DOSE BISOPROLOL/HYDROCHLOROTHIAZIDE COMBINATION IN PATIENTS WITH ARTERIAL HYPERTENSION OF 1-2 DEGREES. RESULTS OF CLINICAL RANDOMIZED CROSSOVER STUDY

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To study the clinical equivalence of the two low-dose combined drugs on the base of generic and original bisoprolol and hydrochlorothiazide (HCTZ): BISANGIL® (Ozon, Russia) and LODOZ® (NYCOMED, Merck KGaA, Germany) in patients with arterial ...
S. Yu. Martsevich   +7 more
doaj   +1 more source

THE PROBLEM OF MEDICINES INTERCHANGEABILITY. FOCUS ON PERINDOPRIL

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To evaluate the therapeutic equivalence between generic perindopril (Parnavel, LLC Ozone, Russia) and the original perindopril (Prestarium A, Laboratories Servier, France). Material and methods.
A. I. Malyhina   +4 more
doaj   +1 more source

EFFICACY AND TOLERABILITY OF GENERIC ZOLEDRONIC ACID 5 MG (REZOCLASTIN PS) IN THE TREATMENT OF OSTEOPOROSIS: A RETROSPECTIVE ANALYSIS OF CLINICAL EXPERIENCE WITH THE DRUG IN RUSSIA

open access: yesОстеопороз и остеопатии, 2014
Objectives. To analyze clinical data of the first domestic zoledronic acid generic preparation for the treatment of osteoporosis (Rezoclastin PS., 5 mg). Materials and Methods.
L A Marchenkova, A V Dreval, I V Baharev
doaj   +1 more source

RAVNITEL'NAYa OTsENKA PERENOSIMOSTI PREPARATOV ZOLEDRONOVOY KISLOTY

open access: yesОстеопороз и остеопатии, 2016
Несмотря на высокую распространенность и социально-экономическую значимость остеопороза (ОП), в России больные ОП в большинстве случаев не получают бесплатного лекарственного обеспечения, что в свою очередь приводит к нерегулярному приему лекарственных ...
N V BEZLYuDNAYa   +4 more
doaj   +1 more source

HPLC determination, pharmacokinetics and relative bioavailability of levofloxacin produced by «OZONE», Russia

open access: yesФармакокинетика и Фармакодинамика, 2013
A simple, specific, sensitive and reproducible good method for quantitative determination of Levofloxacin in plasma using HPLC with UV-spectrophotometric detection. With this technique the pharmacokinetics and relative bioavailability of domestic generic
S. N. Kondratenko   +4 more
doaj  

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