Results 1 to 10 of about 36 (36)

THE KARDIOKANON STUDY: A WAY TO SETTLE THE SUBJECT OF CLINICAL EQUIVALENCE OF GENERIC AND ORIGINAL DRUGS

Рациональная фармакотерапия в кардиологии, 2015
Aim. To compare two therapies based on the use of original or generic drugs in patients with stable ischemic heart disease (IHD). Material and methods.
S. Yu. Martsevich, N. P. Kutishenko, M. L. Ginzburg, G. V. Matyushin, V. V. Skibitskiy, L. A. Sokolova, A. V. Deev   +6 more
doaj   +1 more source

STATIN GENERICS: EFFICACY AND SAFETY RATIO

Рациональная фармакотерапия в кардиологии, 2016
Statin usage for primary and secondary prevention of cardiovascular diseases is focused. Rational choice between original and generic drugs is discussed taking into account efficacy and safety ratio.
V. P. Voronina, A. A. Serazhim, A. V. Zagrebelnyi, S. Yu. Martsevich, S. A. Shalnova   +4 more
doaj   +1 more source

THE PROBLEM OF MEDICINES INTERCHANGEABILITY. FOCUS ON PERINDOPRIL

Рациональная фармакотерапия в кардиологии, 2015
Aim. To evaluate the therapeutic equivalence between generic perindopril (Parnavel, LLC Ozone, Russia) and the original perindopril (Prestarium A, Laboratories Servier, France). Material and methods.
A. I. Malyhina, M. V. Zhuravleva, A. K. Starodubtsev, M. L. Maksimov, O. A. Rogacheva   +4 more
doaj   +1 more source

ASSESSMENT OF THERAPEUTICAL EQUIVALENCY OF ORIGINAL AND GENERIC INDAPAMIDE IN HYPERTENSIVE PATIENTS BY RANDOMIZED CROSS-OVER STUDY

Рациональная фармакотерапия в кардиологии, 2015
Aim. To develop a protocol for comparison of efficacy and safety of original drugs with generic ones and to apply this protocol for comparison of generic indapamide (Indap) with original indapamide in two presentations: short acting (Arifon) and long ...
N. P. Kutishenko, V. V. Yakusevich, A. D. Deev, S. Y. Martsevich   +3 more
doaj   +1 more source

Выбор препарата для лекарственной терапии с учетом особенностей субстанции

Архивъ внутренней медицины, 2012
The article presents current data about the features of the drug production considering substance quality. It was investigated the advantages and disadvantages of various original and generic drugs, include hepatoprotectors.
С. С. Вялов, А. А. Степченко, Т. А. Дронова, Е. В. Винницкая   +3 more
doaj   +1 more source

THERAPEUTIC EQUIVALENCE OF ORIGINAL CLOPIDOGREL (PLAVIX) AND ITS GENERIC (EGITROMB). RESULTS OF COMPARATIVE RANDOMIZED CROSS-OVER BLIND STUDY

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study therapeutic equivalence (efficacy, safety and tolerability) of original clopidogrel (Plavix) and its generic (Egitromb) in patients of high cardiovascular risk. Material and methods.
V. V. Yakusevich, A. S. Petrochenko, V. A. Simonov, N. Yu. Levshin, A. D. Deev   +4 more
doaj   +1 more source

UP TO DATE ANTIPLATELET THERAPY IN PATIENTS WITH HIGH RISK OF THROMBOTIC EVENTS AND REAL CLINICAL PRACTICE

Рациональная фармакотерапия в кардиологии, 2015
Aim. To assess the real rate of dual antiplatelet therapy (DAT, acetylsalicylic acid + clopidogrel) use in patients having appropriate indications according to current clinical guidelines and to study the possibility of prescription rate improvement by ...
S. Yu. Martsevich, V. P. Voronina, M. L. Ginzburg, N. P. Kutishenko, Yu. N. Polyanskaya, T. G. Kheliya, A. M. Malysheva, S. N. Tolpygina, V. S. Kutuzova, E. A. Gofman, A. D. Deev   +10 more
doaj   +1 more source

COMPARATIVE EVALUATION OF EFFICACY AND TOLERABILITY OF ORIGINAL AND GENERIC BISOPROLOL IN PATIENTS WITH ARTERIAL HYPERTENSION 1-2 GRADE

Рациональная фармакотерапия в кардиологии, 2015
Aim. To study a clinical equivalence of two medications of bisoprolol in patients with arterial hypertension (AH) 1-2 grades.Methods. Efficacy and tolerability of original (Concor, NYCOMED, Merck KGaA) and generic (Bisogamma, WORWAG PHARMA GmbH & Co)
S. N. Tolpygina, E. V. Shilova, S. Y. Martsevich   +2 more
doaj   +1 more source

CLINICAL AND PHARMACOKINETIC EQUIVALENCE OF ORIGINAL AND GENERIC AMLODIPINE IN PATIENTS WITH MILD-TO-MODERATE ARTERIAL HYPERTENSION

Рациональная фармакотерапия в кардиологии, 2015
Aim. To study clinical equivalence of two amlodipines under the control of their plasma levels and evaluate their pharmacoeconomical efficacy in patients with arterial hypertension (AH).Material and methods. 31 patient with AH were included in the study (
N. A. Belolipetskiy, S. N. Tolpygina, J. B. Zverkov, V. V. Pisarev, I. E. Koltunov, V. G. Belolipetskaya, S. J. Martsevich   +6 more
doaj   +1 more source

Choosing a systemic antifungal agent for the treatment of vaginal candidiasis: original or generic fluconazole?

Медицинский совет, 2015
The article tells about the main guidelines for choosing a systemic antifungal agent containing fluconazole from those present on the Russian market of medicinal products. Results of comparing original and generic fluconazole medicines are demonstrated.
А. S. Dukhanin
doaj   +1 more source